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低钠血症流行:是遥不可及的前沿领域吗?

The Hyponatremia Epidemic: A Frontier Too Far?

作者信息

Drake-Holland Angela J, Noble Mark I M

机构信息

School of Pharmacy and Life Sciences, The Robert Gordon University , Aberdeen , UK.

Department of Medicine and Therapeutics, University of Aberdeen , Aberdeen , UK.

出版信息

Front Cardiovasc Med. 2016 Oct 7;3:35. doi: 10.3389/fcvm.2016.00035. eCollection 2016.

Abstract

Hyponatremia is the most common electrolyte abnormality and is often neglected, especially in elderly and seemingly terminal patients. Hyponatremia can be asymptomatic or can cause symptoms ranging from nausea and lethargy to convulsions and coma. This condition has become increasingly common over time with a similar time course to the increase in adoption of low salt diets. The popularization of low salt may not be justified in people with normal kidney function in whom the compatible statistically based evidence that salt causes hypertension has been challenged by experimental evidence to the contrary.

摘要

低钠血症是最常见的电解质异常情况,且常常被忽视,尤其是在老年患者和看似处于终末期的患者中。低钠血症可能没有症状,也可能引发从恶心、嗜睡到惊厥和昏迷等一系列症状。随着时间的推移,这种情况越来越普遍,其时间进程与低盐饮食采用率的增加相似。对于肾功能正常的人来说,低盐饮食的普及可能并无依据,因为基于统计学的、认为盐会导致高血压的证据已受到相反实验证据的质疑。

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