Munetsugu Takichi, Fujimoto Tomoko, Oshima Yuichiro, Sano Kenji, Murota Hiroyuki, Satoh Takahiro, Iwase Satoshi, Asahina Masato, Nakazato Yoshihiko, Yokozeki Hiroo
Department of Dermatology, Tokyo Medical and Dental University, Tokyo, Japan.
Department of Dermatology, National Defense Medical College, Saitama, Japan.
J Dermatol. 2017 Apr;44(4):394-400. doi: 10.1111/1346-8138.13649. Epub 2016 Oct 24.
Acquired idiopathic generalized anhidrosis (AIGA) is characterized by an acquired impairment in total body sweating despite exposure to heat or exercise. Severe cases may result in heatstroke. Most cases of AIGA have been reported in Asia, especially in Japan. However, there is limited information on the epidemiology of this condition, and no diagnostic criteria or appropriate treatment options have been established. This guideline was developed to fill this gap. It contains information on the etiology, diagnosis, evaluation of disease severity and evidence-based recommendations for the treatment of AIGA. Appropriate treatment according to disease severity may relieve the clinical manifestations and emotional distress experienced by patients with AIGA.
获得性特发性全身性无汗症（AIGA）的特征是，即便暴露于高温环境或进行运动，全身出汗功能仍出现后天性损害。严重病例可能导致中暑。AIGA的大多数病例报告来自亚洲，尤其是日本。然而，关于这种病症的流行病学信息有限，尚未确立诊断标准或合适的治疗方案。本指南旨在填补这一空白。它包含有关AIGA的病因、诊断、疾病严重程度评估以及循证治疗建议的信息。根据疾病严重程度进行适当治疗，可缓解AIGA患者的临床表现和情绪困扰。
