Pont Lisa G, Morgan Tessa K, Williamson Margaret, Haaijer Flora M, van Driel Mieke L
Centre for Health Systems and Safety Research, Australian Institute of Health Innovation, Macquarie University, North Ryde, NSW, Australia.
NPS MedicineWise, Sydney, NSW, Australia.
Int J Pharm Pract. 2017 Feb;25(1):66-74. doi: 10.1111/ijpp.12318. Epub 2016 Oct 24.
The aim of this study was to assess the validity of a set of European quality indicators for assessing antimicrobial prescribing in Australian General Practice.
A modified UCLA/RAND appropriateness method was used to assess the validity of 30 antimicrobial prescribing indicators. An expert panel of 12 general practitioners scored the validity of each indicator for measuring quality in Australian general practice. Four quality domains were considered: monitoring antibiotic resistance, benefit to individual patients, value for money and value to policymakers. Panel members were also asked to comment on the relevance to the Australian context and proposed benchmarks for each indicator.
All panel members were in agreement regarding the validity of each indicator in each of the specified domains with exception of the indicator assessing the use of systemic antibiotics for pneumonia. The majority of the indicators and their associated benchmarks were considered valid for assessing quality in Australian General Practice, however, there were differences regarding the quality domain that each indicator was considered valid for. Monitoring quality considering individual patient benefit was the most problematic domain with respect to validity.
This study demonstrates the validity of 30 European indicators for assessing quality of antimicrobial prescribing in general practice in a non-European setting and provides guidance regarding acceptable benchmarks for the indicators. With international concerns regarding misuse of antibiotics and global interest in prescribing quality, valid evidence-based antimicrobial prescribing indicators and associated benchmarks are an essential tool for assessing prescribing quality.
本研究旨在评估一套欧洲质量指标在澳大利亚全科医疗中用于评估抗菌药物处方的有效性。
采用改良的加州大学洛杉矶分校/兰德适用性方法评估30项抗菌药物处方指标的有效性。一个由12名全科医生组成的专家小组对每项指标在衡量澳大利亚全科医疗质量方面的有效性进行评分。考虑了四个质量领域:监测抗生素耐药性、对个体患者的益处、性价比以及对政策制定者的价值。小组成员还被要求就这些指标与澳大利亚实际情况的相关性发表评论,并为每项指标提出基准。
除了评估用于治疗肺炎的全身用抗生素使用情况的指标外,所有小组成员对于每个指定领域中每项指标的有效性都达成了一致。大多数指标及其相关基准被认为可有效评估澳大利亚全科医疗的质量,然而,每项指标被认为有效的质量领域存在差异。就有效性而言,考虑个体患者益处的质量监测领域问题最大。
本研究证明了30项欧洲指标在非欧洲环境下用于评估全科医疗中抗菌药物处方质量的有效性,并为这些指标的可接受基准提供了指导。鉴于国际上对抗生素滥用的关注以及全球对处方质量的兴趣,有效的循证抗菌药物处方指标及相关基准是评估处方质量的重要工具。