Tylkowski Bartosz, Nowak Martyna, Tsibranska Irene, Trojanowska Anna, Marciniak Lukasz, Valls Ricard Garcia, Gumi Tania, Giamberini Marta, Jastrząb Renata
Centre Tecnològic de la Química de Catalunya, Carrer de Marcel·lí Domingo, 43007 Tarragona, Spain.
Faculty of Chemistry, Adam Mickiewicz University, Umultowska 89b, 61-614, Poznan, Poland.
Curr Pharm Des. 2017;23(2):231-241. doi: 10.2174/1381612822666161021124358.
This review aims to present the relevant background information and current research status in concentration of polyphenols using membrane technologies. The potential implementation of membrane separation to bioactive compounds like soluble phenolics from aqueous and organic solvent solutions is gaining increasing interest in the recent years. This review does not pretend to cover the abundant published literature on the subject, but to be representative for the observed tendencies in membrane processes applications for concentration of polyphenols derived from natural products. The first part of the article includes general information regarding the polyphenols and the traditional methods for their separation (such as: thin layer chromatography; paper chromatography; gas chromatography; high performance liquid chromatography; capillary electrophoresis), while the second part presents a review of different membrane processes applied for concentration of polyphenols. Three main sources for such implementations are discussed: (1) aqueous or organic solvent extracts from plant material, (2) fruits, and (3) recovery of polyphenols from industrial waste liquids. A diversity of membrane processes are considered in a large scope of implementations ranging from lab-scale studies to pilot and semiindustrial scale operations.
Membrane technology is an excellent candidate to make a paradigm shift in biological active compounds fractionation/separation processes. Presented results clearly demonstrate that membrane processes are of great advantages over traditionally used methods; however, characterization of separated polyphenols has to be improved. Most of citied authors concentrated their investigation only on the total amount of polyphenols determination. Exhaustive studies including: antioxidant activities, retention index, total soluble solids, or volume reduction factor, have been only carried out by a few authors.
本综述旨在介绍利用膜技术浓缩多酚的相关背景信息和当前研究现状。近年来，膜分离技术在从水相和有机溶剂溶液中分离生物活性化合物（如可溶性酚类）方面的潜在应用越来越受到关注。本综述并非要涵盖该主题已发表的大量文献，而是要代表膜过程在浓缩天然产物中多酚应用方面的观察趋势。文章的第一部分包括关于多酚的一般信息及其传统分离方法（如：薄层色谱法；纸色谱法；气相色谱法；高效液相色谱法；毛细管电泳法），而第二部分则对用于浓缩多酚的不同膜过程进行了综述。讨论了此类应用的三个主要来源：（1）植物材料的水相或有机溶剂提取物，（2）水果，以及（3）从工业废液中回收多酚。在从实验室规模研究到中试和半工业规模操作的广泛应用范围内，考虑了多种膜过程。
膜技术是在生物活性化合物分级/分离过程中实现范式转变的极佳选择。所呈现的结果清楚地表明，膜过程相对于传统使用的方法具有很大优势；然而，分离出的多酚的表征必须得到改进。大多数被引用的作者仅将研究集中在多酚总量的测定上。只有少数作者进行了详尽的研究，包括：抗氧化活性、保留指数、总可溶性固形物或体积减少因子。
