Department of Chemistry and Biochemistry, National Chung Cheng University , 168 University Road, Minhsiung, Chiayi 62102, Taiwan, Republic of China.
Chemical Systems Research Division, National Chung-Shan Institute of Science and Technology , Taoyuan 32599, Taiwan , Republic of China.
Anal Chem. 2016 Nov 15;88(22):10837-10841. doi: 10.1021/acs.analchem.6b02707. Epub 2016 Nov 1.
We demonstrated here a successful development of the use of functional ionic liquids FIL 1 and FIL 3 for chemoselective detection of alkene gases measured by quartz crystal microbalance. This detection of gaseous alkenes was achieved by the Diels-Alder [4 + 2] cycloadditions with FIL 1 and FIL 3 thin-coated on quartz chips. Our functional ionic liquids could be prepared by straightforward synthetic chemistry in short steps and are superior in alkene gas detection. The QCM platform developed in this work is chemoselective with fast gas diffusion into ionic liquids, readily applicable to low molecular weight alkene gases and insensitive to moisture. To the best of our knowledge, this is the first report based upon the Diels-Alder reactions demonstrating sensitive alkene gas detection in ionic liquids on a QCM. This work is a proof-of-concept inspection of the promising use of a QCM-based sensor method for reaction-directed detection of gas samples, which is part of an ongoing program aimed at studying diseases.
我们在此展示了功能离子液体 FIL1 和 FIL3 在通过石英晶体微天平测量的烯烃气体的化学选择性检测中的成功应用。通过与 FIL1 和 FIL3 的 Diels-Alder [4+2]环加成反应，实现了对气态烯烃的检测，这些 FIL1 和 FIL3 被薄涂在石英芯片上。我们的功能离子液体可以通过简单的合成化学在短步骤中制备，并且在烯烃气体检测方面具有优势。本工作中开发的 QCM 平台具有化学选择性，气体可以快速扩散到离子液体中，易于应用于低分子量烯烃气体，并且对水分不敏感。据我们所知，这是第一个基于 Diels-Alder 反应的报告，证明了在 QCM 上的离子液体中对敏感烯烃气体的检测。这项工作是对基于 QCM 的传感器方法用于反应导向的气体样品检测的有前途用途的概念验证检查，这是旨在研究疾病的正在进行的计划的一部分。
