a Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam, South Korea.
b Seoul National University Hospital , Seoul , South Korea.
Ocul Immunol Inflamm. 2018;26(4):639-641. doi: 10.1080/09273948.2016.1239744. Epub 2016 Oct 24.
To report a case of a choroidal neovascularization (CNV) secondary to ocular toxocariasis treated with intravitreal injections of anti-vascular endothelial growth factor (VEGF) agents.
A 66-year-old woman presented with decreased vision (20/40) and metamorphopsia in the right eye. Fundus examination revealed inferotemporal retinal whitish lesion and subretinal hemorrhage in the right eye.
She was diagnosed with ocular toxocariasis based on the clinical features and positive serological anti-toxocara antibody test result. Ophthalmic examination revealed classic CNV formation adjacent to a retinal granuloma. She was treated with intravitreal ranibizumab and bevacizumab injections combined with oral albendazole. Her vision decreased to 20/100 following CNV recurrence. However, after additional bevacizumab treatment, the CNV became inactive and her vision recovered to 20/40.
CNV can be combined with retinal granuloma due to ocular toxocariasis. Repeated intravitreal injections of anti-VEGF agents can be efficacious for regressing toxocariasis-associated CNV and improving vision.
报告一例眼弓蛔虫病继发脉络膜新生血管（CNV）经抗血管内皮生长因子（VEGF）药物玻璃体腔内注射治疗的病例。
一名 66 岁女性因右眼视力下降（20/40）和视物变形就诊。眼底检查显示右眼颞下视网膜灰白色病变和视网膜下出血。
根据临床特征和血清抗弓蛔虫抗体阳性结果，诊断为眼弓蛔虫病。眼部检查显示典型的 CNV 紧邻视网膜肉芽肿形成。她接受了玻璃体腔内雷珠单抗和贝伐单抗注射联合口服阿苯达唑治疗。继 CNV 复发后，她的视力下降至 20/100。然而，在额外接受贝伐单抗治疗后，CNV 活动减少，视力恢复至 20/40。
CNV 可与眼弓蛔虫病的视网膜肉芽肿合并存在。反复玻璃体腔内注射抗 VEGF 药物对视弓蛔虫病相关 CNV 的消退和视力的提高可能有效。
