Pappalardo G, Caltabiano M, Gulisano S
Minerva Stomatol. 1978 Apr-Jun;27(2):95-9.
The pattern of experimental caries was examined in rats treated with magnesium fluosilicate associated with manganese and a cariogenic diet. A 33.34% fall in the incidence of caries was observed with respect to a control series, whereas Mg fluosilicate and manganese administered alone caused 30% and 20% reductions respectively. It was also noted that a slight toxic action, expressed as a 3 g fall in body weight, was found with the Mg fluosilicate dose employed; this effect was attenuated by simultaneous administration of manganese.
在食用致龋饮食的大鼠中，研究了用氟硅酸镁与锰联合处理后的实验性龋齿模式。与对照组相比，龋齿发病率下降了33.34%，而单独使用氟硅酸镁和锰分别使龋齿发病率降低了30%和20%。还注意到，所使用的氟硅酸镁剂量存在轻微毒性作用，表现为体重下降3克；同时给予锰可减轻这种作用。
