基于单链和双链阳离子表面活性剂的凝聚萃取。
A coacervative extraction based on single-chain and double-chain cationic surfactants.
作者信息
Kukusamude Chunyapuk, Quirino Joselito P, Srijaranai Supalax
机构信息
Materials Chemistry Research Center, Department of Chemistry and Center of Excellence for Innovation in Chemistry, Faculty of Science, Khon Kaen University, Khon Kaen 40002, Thailand.
Australian Centre for Research on Separation Science (ACROSS), School of Physical Sciences-Chemistry, University of Tasmania, Hobart 7001, Australia.
出版信息
J Chromatogr A. 2016 Nov 11;1472:10-15. doi: 10.1016/j.chroma.2016.10.030. Epub 2016 Oct 12.
A coacervative extraction (CAE) with the common cationic surfactants dodecyltrimethylammonium bromide (DTAB) and didodecyldimethylammonium bromide (DDAB) was firstly developed. Notable characteristics of the CAE was the use of low concentration of salt (0.1molL NaBr) at ambient temperature and without the requirement of organic solvent. The CAE was based on phase separation due to the neutralization of the surface charge of the micelle by electrostatic interaction with the predominant common counter ion (bromide). The coacervative phase was subjected to an optimized micellar liquid chromatography with UV (MLC-UV) method without any treatments. The method was applied to the determination of penicillins including amoxicillin, ampicillin, penicillin-G, oxacillin, and cloxacillin in milk samples. Method detection limits (MDLs) from standard were 0.5-2ngmL, and 40-80-fold analyte enrichment were obtained. The CAE-MLC-UV has shown to be of high potential for the analysis of five penicillins in milk with recoveries >90%.
首次开发了一种使用常见阳离子表面活性剂十二烷基三甲基溴化铵（DTAB）和二甲基二癸基溴化铵（DDAB）的凝聚萃取（CAE）方法。CAE的显著特点是在室温下使用低浓度盐（0.1mol/L NaBr）且无需有机溶剂。CAE基于胶束表面电荷与主要常见抗衡离子（溴离子）通过静电相互作用而中和导致的相分离。凝聚相未经任何处理直接采用优化的胶束液相色谱 - 紫外（MLC - UV）方法。该方法用于测定牛奶样品中的青霉素，包括阿莫西林、氨苄西林、青霉素G、苯唑西林和氯唑西林。标准方法检测限（MDLs）为0.5 - 2ng/mL，实现了40 - 80倍的分析物富集。CAE - MLC - UV已显示出在分析牛奶中五种青霉素方面具有很高的潜力，回收率>90%。
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