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肉毒杆菌A毒素治疗口下颌肌张力障碍:一系列病例

Management of oromandibular dystonia with botulinum A toxin: a series of cases.

作者信息

Teemul T A, Patel R, Kanatas A, Carter L M

机构信息

Leeds Teaching Hospitals NHS Trust, Leeds Dental Institute, Clarendon Way, Leeds LS2 9LU, United Kingdom.

出版信息

Br J Oral Maxillofac Surg. 2016 Dec;54(10):1080-1084. doi: 10.1016/j.bjoms.2016.06.028. Epub 2016 Oct 21.

Abstract

Oromandibular dystonia is a disorder of movement that is often misdiagnosed. We present our experience of six patients treated with botulinum A toxin, for whom we recorded the symptoms, the group of muscles targeted, and the quantity of botulinum toxin used. We used the Glasgow Benefit Inventory (GBI) questionnaire to record and analyse outcomes after treatment. Five of the six patients had a good outcome as recorded by the GBI, the mean (SD) score of which was +40 (28), which reflected that the patients were well satisfied. The overall improvement in the categories of general health, social health, and physical health were 82%, 37%, and 31%, respectively. Botulinum type A toxin is an effective treatment of oromandibular dystonia. It is important for clinicians to recognise the condition, as treatment is well-tolerated and can improve quality of life.

摘要

口下颌肌张力障碍是一种常被误诊的运动障碍疾病。我们介绍了6例接受A型肉毒毒素治疗患者的情况,记录了他们的症状、靶向肌肉群以及所用肉毒毒素的剂量。我们使用格拉斯哥疗效量表(GBI)问卷记录并分析治疗后的结果。GBI记录显示,6例患者中有5例疗效良好,其平均(标准差)得分为+40(28),这表明患者满意度较高。总体健康、社会健康和身体健康类别的改善率分别为82%、37%和31%。A型肉毒毒素是治疗口下颌肌张力障碍的有效方法。临床医生认识到这种疾病很重要,因为该治疗耐受性良好且可改善生活质量。

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