[Effect of cultivation temperature and pH on the biosynthesis of extracellular phosphohydrolases by the culture Penicillium brevi-compactum].

The effect of cultivation temperature and pH on growth of the culture Penicillium brevi-compactum and biosynthesis of extracellular phosphohydrolases (acid and alkaline RNases and acid PMEase) involved in RNA degradation was studied. The maximum growth of the culture was seen at 30 degrees and pA-7.0 and its maximum physiological activity with respect to the above enzymes was noted at 24 degrees and pH = 3.0, i.e. optimal conditions for the biosynthesis of phosphohydrolases did not coincide with those for the culture growth. The cultivation temperature and pH produced an effect on the oxygen consumption and synthesis of extracellular phosphohydrolases by the culture.