[Selection of cultures of microscopic fungi synthesizing phosphomonoesterase inhibitors].

The work was aimed at studying the ability of Aspergillus and Penicillium species to isolate phosphomonoesterases (PMEases) in the cultural broth in the course of submerged cultivation in a complex nutrient medium. The cultures produced both acid and alkaline PMEases, but acid PMEase was produced at a much greater rate than alkaline PMEase. The activity of acid and alkaline PMEases decreased in most cases when the cultural broth and cell-free extracts were incubated with urea. The activity of exocellular acid PMEases was inhibited by the cell-free extracts of most cultures. The inhibition of PMEases from different sources is manifested in the studied cultures of Aspergillus and Penicillium in a different manner.