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开发一种用作补体结合试验中介体的单克隆抗体。

Development of a monoclonal antibody for use as an amboceptor in complement fixation tests.

作者信息

Ossewaarde J M, de Booij A D

机构信息

Laboratory of Virology, National Institute of Public Health and Environmental Protection, Bilthoven, The Netherlands.

出版信息

J Virol Methods. 1989 Jul;25(1):13-20. doi: 10.1016/0166-0934(89)90096-7.

Abstract

A monoclonal antibody for use as a haemolytic amboceptor in complement fixation tests was developed. The monoclonal antibody selected was investigated in parallel with conventional rabbit amboceptor. The results with the monoclonal amboceptor were at least as good as with the rabbit amboceptor. Production of the monoclonal amboceptor was attained provided that hybridoma growth factor was added to the culture medium.

摘要

开发了一种用于补体结合试验中作为溶血介体的单克隆抗体。所选择的单克隆抗体与传统兔介体同时进行研究。单克隆介体的结果至少与兔介体的结果一样好。只要在培养基中添加杂交瘤生长因子,就能实现单克隆介体的生产。

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