Jung Jin Tae
Department of Internal Medicine, Catholic University of Daegu School of Medicine, Daegu, Korea.
Korean J Gastroenterol. 2016 Oct 25;68(4):175-178. doi: 10.4166/kjg.2016.68.4.175.
Gastric mucosa-associated lymphoid tissue (MALT) lymphoma is associated with infection. eradication can be performed as a primary therapy regardless of status. In Korea, six articles were published about low-grade gastric MALT lymphoma with . Complete regression rate after eradication is reported at 74.5% to 94.4%. Radiotherapy results in favorable clinical long-term outcomes in patients with early-stage gastric MALT lymphoma who fail eradication therapy and those who are negative. Chemotherapy could be reserved for patients with metastatic or high-grade lymphoma. In gastric MALT lymphoma, patients with polypoid type on initial endoscopy had a higher likelihood of recurrence than those with diffuse infiltration or ulceration types. The depth of invasion, location of lesions, and chromosomal abnormality with t(11;18) together are predictive factors for failure to remission by eradication.
胃黏膜相关淋巴组织（MALT）淋巴瘤与感染有关。无论分期如何，根除治疗均可作为主要治疗方法。在韩国，发表了6篇关于伴有幽门螺杆菌感染的低级别胃MALT淋巴瘤的文章。据报道，根除幽门螺杆菌后的完全缓解率为74.5%至94.4%。对于根除治疗失败且幽门螺杆菌阴性的早期胃MALT淋巴瘤患者，放疗可带来良好的临床长期疗效。化疗可用于转移性或高级别淋巴瘤患者。在胃MALT淋巴瘤中，初始内镜检查为息肉样类型的患者比弥漫浸润型或溃疡型患者复发的可能性更高。侵袭深度、病变位置以及伴有t(11;18)的染色体异常共同是根除治疗未能缓解的预测因素。
