1958 - 1976年瑞士欧洲散发性牛脑炎历史病例中星状病毒的检测
Detection of Astrovirus in Historical Cases of European Sporadic Bovine Encephalitis, Switzerland 1958-1976.
作者信息
Selimovic-Hamza Senija, Bouzalas Ilias G, Vandevelde Marc, Oevermann Anna, Seuberlich Torsten
机构信息
DCR-VPH, Division of Neurological Sciences, NeuroCenter, University of Bern, Bern, Switzerland; Graduate School for Cellular and Biomedical Sciences, University of Bern, Bern, Switzerland.
DCR-VPH, Division of Neurological Sciences, NeuroCenter, University of Bern , Bern , Switzerland.
出版信息
Front Vet Sci. 2016 Oct 11;3:91. doi: 10.3389/fvets.2016.00091. eCollection 2016.
European sporadic bovine encephalitis is a frequent diagnosis in neurologically diseased cattle, but its etiology remained unresolved. Using hybridization, we have detected a recently discovered neurotropic bovine astrovirus in historical tissues in a high proportion of brain samples of affected cattle. Our results suggest that astroviruses were already involved in the pathogenesis of the disease several decades ago, but have gone undetected.
欧洲散发性牛脑炎是神经疾病牛群中常见的诊断病症，但其病因仍未明确。通过杂交技术，我们在患病牛的大部分脑样本的历史组织中检测到了一种最近发现的嗜神经性牛星状病毒。我们的结果表明，星状病毒在几十年前就已参与该疾病的发病机制，但一直未被发现。
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