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肺部超声:监测重症患者呼吸机相关性肺炎的一种有前景的工具。

Lung ultrasound: a promising tool to monitor ventilator-associated pneumonia in critically ill patients.

作者信息

Wang Guyi, Ji Xiaoying, Xu Yongshan, Xiang Xudong

机构信息

Department of Intensive Care Unit, The Second Xiangya Hospital, Central South University, Changsha City, Hunan Province, China.

Department of General Intensive Care Unit, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.

出版信息

Crit Care. 2016 Oct 27;20(1):320. doi: 10.1186/s13054-016-1487-y.

Abstract

Ventilator-associated pneumonia (VAP) is the most frequent intensive care unit (ICU)-acquired infection that is independently associated with mortality. Accurate diagnosis and timely treatment have been shown to improve the prognosis of VAP. Chest X-ray or computed tomography imaging are used for conventional assessment of VAP, but these methods are impractical for real-time measurement in critical patients. Therefore, lung ultrasound (LUS) has been increasingly used for the assessment of VAP in the ICU. Traditionally, LUS has seemed unsuitable for the detection of lung parenchyma owing to the high acoustic impedance of air; however, the fact that the reflection and reverberation in the detection region of the ultrasound reflect the underlying pathology of lung diseases has led to the increased use of ultrasound imaging as a standard of care supported by evidence-based and expert consensus in the ICU. Considering that any type of pneumonia causes air volume changes in the lungs, accumulating evidence has shown that LUS effectively measures the presence of VAP as well as dynamic changes in VAP. This review offers evidence for ultrasound as a noninvasive, easily repeatable, and bedside means to assess VAP; in addition, it establishes a protocol for qualitative and quantitative monitoring of VAP.

摘要

呼吸机相关性肺炎(VAP)是重症监护病房(ICU)获得性感染中最常见的类型,且与死亡率独立相关。已证实准确诊断和及时治疗可改善VAP的预后。胸部X线或计算机断层扫描成像用于VAP的常规评估,但这些方法对于危重症患者的实时测量并不实用。因此,肺部超声(LUS)在ICU中越来越多地用于VAP的评估。传统上,由于空气的高声阻抗,LUS似乎不适用于检测肺实质;然而,超声检测区域中的反射和混响反映了肺部疾病的潜在病理这一事实,导致超声成像作为一种在ICU中得到循证医学和专家共识支持的标准治疗手段的应用增加。鉴于任何类型的肺炎都会导致肺部气量变化,越来越多的证据表明LUS能有效检测VAP的存在以及VAP的动态变化。本综述为超声作为一种评估VAP的非侵入性、易于重复且可在床边进行的手段提供了证据;此外,还建立了VAP定性和定量监测的方案。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b394/5081926/611c28d1e493/13054_2016_1487_Fig1_HTML.jpg

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