Li Hai-Yun, Cheng Cong-Yuan
Nanyang Blood Center, Nanyang 473000, Henan Province, China. E-mail:
Nanyang Blood Center, Nanyang 473000, Henan Province, China.
Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2016 Oct;24(5):1583-1587. doi: 10.7534/j.issn.1009-2137.2016.05.054.
To understand the regularity of Rh blood typing of valunteary blood donors in Chinese Nanyang city, and to estabbish a Rh DC/c/E/e antigen negative donor base so as to provide the help for clinical emergent blood transfusion to patients and ensure the safety of blood transfusion.
The Rh D blood group of blood samples from 81462 voluntary blood donors in Chinese Nanyang city in 2014 was identified by serologic method; after first screening and confirmation, the RhE/e/C/c typing of Rh D negative samples was performed; the detailed infornation of donors was registered seriously by using unified creteria; the data base and base in kind of RhE/e/C/c types of valuntary donors were established by means of compater-mamayement system.
300 cases (0.37%) were RhD negative blood donors, and the Rh antigen was Ccdee and ccdee in 83%.
The proportion of RhD negative donors accounts for 4% of Chinese Nanyang peoples, the RhE/e/C/c types of RhD negative donors are ccdee (50.67%)>Ccdee (33.00%)>ccdEe(5.67%)>CCdee (5.33%)>CcdEe(5.33%). The establisment of RhE/e/C/c subbase can show importent significance for clinical blood transfusion.
了解中国南阳地区无偿献血者Rh血型分布规律，建立Rh DC/c/E/e抗原阴性献血者库，为临床抢救患者紧急用血提供保障，确保输血安全。
采用血清学方法对2014年中国南阳地区81462名无偿献血者血样进行Rh D血型鉴定；对Rh D阴性样本进行初筛及确认后，进行RhE/e/C/c定型；按照统一标准认真登记献血者详细信息；利用计算机管理系统建立RhE/e/C/c血型无偿献血者数据库及实物库。
RhD阴性献血者300例（0.37%），其中Rh抗原为Ccdee和ccdee的占83%。
南阳地区RhD阴性献血者占人群比例为4‰，RhD阴性献血者的RhE/e/C/c血型分布为ccdee（50.67%）>Ccdee（33.00%）>ccdEe(5.67%)>CCdee (5.33%)>CcdEe(5.33%)。建立RhE/e/C/c亚型库对临床输血有重要意义。
