Teke Memik, Teke Fatma, Alan Bircan, Türkoğlu Ahmet, Hamidi Cihad, Göya Cemil, Hattapoğlu Salih, Gumus Metehan
Department of Radiology, Medical School, Dicle University, Yenişehir, 21280, Diyarbakır, Turkey.
Department of Radiation Oncology, Medical School, Dicle University, Diyarbakir, Turkey.
J Med Ultrason (2001). 2017 Jan;44(1):109-115. doi: 10.1007/s10396-016-0749-2. Epub 2016 Oct 27.
Differentiation of idiopathic granulomatous mastitis (IGM) from carcinoma with routine imaging methods, such as ultrasonography (US) and mammography, is difficult. Therefore, we evaluated the value of a newly developed noninvasive technique called acoustic radiation force impulse imaging in differentiating IGM versus malignant lesions in the breast.
Four hundred and eighty-six patients, who were referred to us with a presumptive diagnosis of a mass, underwent Virtual Touch tissue imaging (VTI; Siemens) and Virtual Touch tissue quantification (VTQ; Siemens) after conventional gray-scale US. US-guided percutaneous needle biopsy was then performed on 276 lesions with clinically and radiologically suspicious features. Malignant lesions (n = 122) and IGM (n = 48) were included in the final study group.
There was a statistically significant difference in shear wave velocity marginal and internal values between the IGM and malignant lesions. The median marginal velocity for IGM and malignant lesions was 3.19 m/s (minimum-maximum 2.49-5.82) and 5.05 m/s (minimum-maximum 2.09-8.46), respectively (p < 0.001). The median internal velocity for IGM and malignant lesions was 2.76 m/s (minimum-maximum 1.14-4.12) and 4.79 m/s (minimum-maximum 2.12-8.02), respectively (p < 0.001).
The combination of VTI and VTQ as a complement to conventional US provides viscoelastic properties of tissues, and thus has the potential to increase the specificity of US.
采用超声（US）和乳腺X线摄影等常规成像方法鉴别特发性肉芽肿性乳腺炎（IGM）和癌很困难。因此，我们评估了一种新开发的名为声辐射力脉冲成像的非侵入性技术在鉴别乳腺IGM与恶性病变中的价值。
486例因疑似肿块前来就诊的患者在进行常规灰阶超声检查后，接受了虚拟触诊组织成像（VTI；西门子公司）和虚拟触诊组织定量（VTQ；西门子公司）检查。然后对276个具有临床和放射学可疑特征的病变进行了超声引导下经皮穿刺活检。最终研究组纳入了恶性病变（n = 122）和IGM（n = 48）。
IGM与恶性病变之间的剪切波速度边缘值和内部值存在统计学显著差异。IGM和恶性病变的边缘速度中位数分别为3.19 m/s（最小值 - 最大值2.49 - 5.82）和5.05 m/s（最小值 - 最大值2.09 - 8.46）（p < 0.001）。IGM和恶性病变的内部速度中位数分别为2.76 m/s（最小值 - 最大值1.14 - 4.12）和4.79 m/s（最小值 - 最大值2.12 - 8.02）（p < 0.001）。
VTI和VTQ相结合作为传统超声的补充可提供组织的粘弹性特性，因此有可能提高超声的特异性。
