Alper Fatih, Abbasguliyev Hasan, Özmen Sevilay, Yalçin Ahmet, Yılmaz Çankaya Bahar, Akçay Müfide Nuran
Department of Radiology, Atatürk University Faculty of Medicine, Atatürk University Research Hospital, Erzurum, Turkey.
Department of Pathology, Atatürk University Faculty of Medicine, Atatürk University Research Hospital, Erzurum, Turkey.
Eurasian J Med. 2022 Dec;54(Suppl1):172-178. doi: 10.5152/eurasianjmed.2022.22306.
Inflammatory granulomatous mastitis is a benign inflammatory disease of the breast mostly presenting in puerperal women. The disease is characterized by recurrent bouts of mastitis with clinical picture of hyperemia, breast mass, and swelling of the breast with or without purulent discharge depending on the severity of the underlying inflammatory process. Although no true prevalence and incidence have been reported in the literature, there are several reported studies setting forth a predilection in specific ethnic groups and/ or geographical areas. Due to the intricate nature of the disease, quite often inflammatory granulomatous mastitis may be mistaken for malignant processes of the breast and even so, there are no pathognomonic imaging appearances to differentiate one from another. The histopathological analysis is a definite way of diagnosis. In this article, we review the imaging manifestations and clinical and histopathological findings along with current trends of available treatment options in the literature and briefly discussed our institutional perspective regarding grading of inflammatory granulomatous mastitis based on ultrasonographic appearances.
炎性肉芽肿性乳腺炎是一种主要发生于产后女性的乳腺良性炎性疾病。该疾病的特点是乳腺炎反复发作，临床表现为充血、乳腺肿块，以及根据潜在炎症过程的严重程度，乳腺出现肿胀，伴或不伴有脓性分泌物。尽管文献中未报道过该病的真实患病率和发病率，但有几项报道的研究指出了特定种族群体和/或地理区域对该病的偏好。由于该疾病的复杂性，炎性肉芽肿性乳腺炎常常可能被误诊为乳腺恶性病变，即便如此，也没有能够区分两者的特征性影像学表现。组织病理学分析是明确诊断的方法。在本文中，我们回顾了影像学表现、临床及组织病理学发现，以及文献中现有治疗选择的当前趋势，并简要讨论了我们机构基于超声表现对炎性肉芽肿性乳腺炎进行分级的观点。
