Reeves Kenneth Dean, Sit Regina W S, Rabago David P
Private Practice, 4740 El Monte Roeland Park, KS 66205, USA; Department of Physical Medicine and Rehabilitation, University of Kansas Medical Center, 3901 Rainbow Blvd, Kansas City, KS 66160, USA.
The Jockey Club School of Public Health and Primary Care, The Chinese University of Hong Kong, 30-32 Ngan Shing Street, School of Public Health Building, Prince of Wales Hospital, Shatin, New Territory, Hong Kong.
Phys Med Rehabil Clin N Am. 2016 Nov;27(4):783-823. doi: 10.1016/j.pmr.2016.06.001.
Prolotherapy involves the injection of nonbiologic solutions, typically at soft tissue attachments and within joint spaces, to reduce pain and improve function in painful musculoskeletal conditions. A variety of solutions have been used; dextrose prolotherapy is the most rigorously studied and is the focus of this review. Although the mechanism of action is not clearly known, it is likely to be multifactorial. Data on effectiveness for temporomandibular dysfunction are promising but insufficient for recommendations. Research on the mechanism of action and clinical effects of dextrose prolotherapy are under way.
注射疗法涉及将非生物溶液注射到软组织附着处和关节腔内，以减轻疼痛并改善疼痛性肌肉骨骼疾病的功能。已经使用了多种溶液；葡萄糖注射疗法是研究最严格的，也是本综述的重点。虽然作用机制尚不清楚，但可能是多因素的。关于颞下颌关节紊乱症有效性的数据很有前景，但不足以给出推荐。葡萄糖注射疗法的作用机制和临床效果的研究正在进行中。
