Chandran Alagiri, Aswath Nalini
Post Graduate Student, Department of Oral Medicine, Diagnosis and Radiology, Sree Balaji Dental College and Hospital , Chennai, India .
Professor and Head, Department of Oral Medicine, Diagnosis and Radiology, Sree Balaji Dental College and Hospital , Chennai, India .
J Clin Diagn Res. 2016 Sep;10(9):ZC13-ZC15. doi: 10.7860/JCDR/2016/13790.8430. Epub 2016 Sep 1.
Oral Submucous fibrosis (OSMF) is a chronic insidious disease of oral mucosa that occurs due to areca-nut chewing, consumption of chillies, autoimmunity and genetic predisposition. The disease starts with burning sensation and inability to tolerate spicy foods with gradual reduction in mouth opening due to fibrosis of the oral mucosa. The extension of fibrosis into the naso pharynx leads to reduction in hearing efficiency. It is a potentially malignant lesion and can transform into oral cancer.
To assess the functional impairment of eustachian tube by audiogram and tympanometry in both ears in stage IV and stage III OSMF cases.
This was a case-control study in which 30 cases of OSMF, which included 15 stage IV (30 ears), 15 stage III (30 ears) were compared with 15 normal controls.
From this study, it is evident that functions of Eustachian tube were affected as fibrosis of oral mucosa progressed.
口腔黏膜下纤维化(OSMF)是一种口腔黏膜的慢性隐匿性疾病,由咀嚼槟榔、食用辣椒、自身免疫和遗传易感性引起。该病始于烧灼感和无法耐受辛辣食物,随后由于口腔黏膜纤维化导致张口逐渐受限。纤维化延伸至鼻咽部会导致听力效率下降。它是一种潜在的恶性病变,可转变为口腔癌。
通过听力图和鼓室图评估IV期和III期OSMF病例双耳咽鼓管的功能损害。
这是一项病例对照研究,将30例OSMF病例(包括15例IV期,30耳;15例III期,30耳)与15例正常对照进行比较。
1)IV期病例听力图阳性率为76.3%,63.3%的病例鼓膜硬化,即鼓室图呈As曲线;2)III期病例43.3%听力图阳性,46.7%的病例鼓膜硬化,即鼓室图呈As曲线;3)所有对照听力图均为100%阴性,A曲线均正常。
从本研究可知,随着口腔黏膜纤维化的进展,咽鼓管功能受到影响。