Auluck Ajit, Rosin Miriam P, Zhang Lewei, Sumanth K N
Faculty of Dentistry, University of British Columbia, Vancouver, British Columbia.
J Can Dent Assoc. 2008 Oct;74(8):735-40.
Oral submucous fibrosis (OSF) is a premalignant condition mainly associated with the practice of chewing betel quid containing areca nut, a habit common among South Asian people. It is characterized by inflammation, increased deposition of submucosal collagen and formation of fibrotic bands in the oral and paraoral tissues, which increasingly limit mouth opening. Recently, OSF has been reported among South Asian immigrants in Canada, the United Kingdom and Germany. Dentists in western countries should enhance their knowledge of this disease as it seems to be increasing with population migration. In this paper, we review the literature on OSF and present 3 cases representing different stages of the disease to help dentists make an early diagnosis and reduce the morbidity and mortality associated with this condition.
口腔黏膜下纤维化（OSF）是一种主要与咀嚼含槟榔的槟榔块的习惯相关的癌前病变，这种习惯在南亚人群中很常见。它的特征是炎症、黏膜下胶原蛋白沉积增加以及口腔和口周组织中形成纤维化带，这些会逐渐限制张口。最近，在加拿大、英国和德国的南亚移民中也报告了口腔黏膜下纤维化病例。西方国家的牙医应加强对这种疾病的了解，因为随着人口迁移，这种疾病似乎在增加。在本文中，我们回顾了关于口腔黏膜下纤维化的文献，并展示了3例代表该疾病不同阶段的病例，以帮助牙医进行早期诊断，并降低与该疾病相关的发病率和死亡率。
