Institute of Reproductive and Stem Cell Engineering, Basic Medicine College, Central South University, Changsha, Hunan, People's Republic of China.
Reproductive and Genetic Hospital of CITIC-Xiangya, Changsha, Hunan, People's Republic of China.
Fertil Steril. 2017 Jan;107(1):83-88.e2. doi: 10.1016/j.fertnstert.2016.09.035. Epub 2016 Oct 25.
To provide information of semen quality among young Chinese men in the past 15 years.
Retrospective cross-sectional study.
Sperm bank.
PATIENT(S): A total of 30,636 young adult men who applied to be sperm donors at the Hunan Province Human Sperm Bank of China in 2001-2015 were included in the study.
INTERVENTION(S): Physical examination and analysis of blood and semen samples.
MAIN OUTCOME MEASURE(S): Semen parameters, such as semen volume, sperm concentration, total sperm count, progressively motile sperm count, sperm progressive motility, sperm morphology, and round cells.
RESULT(S): Many of the semen parameters showed a decreasing trend over the 15-year observation period. The sperm concentration and percentage of sperm with normal morphology decreased from 68 × 10/mL to 47 × 10/mL and from 31.8% to 10.8%, respectively. Although sperm progressive motility showed irregular variation, the progressively motile sperm count decreased from 34 × 10 to 21 × 10 over the 15-year period. Furthermore, the rate of qualified donors fell from 55.78% in 2001 to 17.80% in 2015, and the rate for 2015 was approximately threefold lower than the corresponding rates in 2001.
CONCLUSION(S): The semen quality among young Chinese men has declined over a period of 15 years, especially in terms of sperm concentration, total sperm count, sperm progressive motility, and normal morphology.
提供过去 15 年中国年轻男性精液质量的信息。
回顾性横断面研究。
精子库。
本研究共纳入 2001 年至 2015 年期间在湖南省人类精子库申请捐精的 30636 名年轻成年男性。
体格检查和血精样本分析。
精液参数，如精液量、精子浓度、总精子数、前向运动精子数、精子前向运动率、精子形态和圆细胞。
在 15 年的观察期内，许多精液参数呈下降趋势。精子浓度和正常形态精子的百分比从 68×10/ml 降至 47×10/ml 和 31.8%降至 10.8%。虽然精子前向运动率呈不规则变化，但 15 年来前向运动精子数从 34×10 降至 21×10。此外，合格供精者的比例从 2001 年的 55.78%降至 2015 年的 17.80%，而 2015 年的比例约为 2001 年的三分之一。
在过去的 15 年里，中国年轻男性的精液质量下降，尤其是精子浓度、总精子数、精子前向运动率和正常形态。
