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一名移植受者发生败血症型类鼻疽,导致移植物功能障碍。

Septicemic melioidosis in a transplant recipient causing graft dysfunction.

作者信息

Sathiavageesan S

机构信息

Department of Medicine, Nephrology Division, Dhanalakshmi Srinivasan Medical College, Perambalur, India; Department of Nephrology, Sundaram Hospital, Tiruchirappalli, Tamil Nadu, India.

出版信息

Indian J Nephrol. 2016 Sep;26(5):379-382. doi: 10.4103/0971-4065.168142.

Abstract

Melioidosis, an infectious disease caused by , is endemic in the Northern Australia and South-East Asia. It is an emerging disease in the Indian subcontinent. Melioidosis tends to run a potentially lethal course in immunocompromised individuals and data in renal transplantation are scarce. The clinical presentation of melioidosis is diverse, mimicking several other infectious diseases. Diagnosis could be delayed in transplant recipients. Choice and duration of antimicrobial therapy, management of immunosuppression, and patient and graft outcomes are other issues to be addressed. We report septicemic melioidosis with pulmonary involvement in a 32-year old renal transplant recipient that caused acute allograft dysfunction.

摘要

类鼻疽病是一种由 引起的传染病,在澳大利亚北部和东南亚地区呈地方性流行。它在印度次大陆是一种新发疾病。类鼻疽病在免疫功能低下的个体中往往会发展为潜在的致命病程,而肾移植方面的数据却很匮乏。类鼻疽病的临床表现多种多样,与其他几种传染病相似。移植受者的诊断可能会延迟。抗菌治疗的选择和疗程、免疫抑制的管理以及患者和移植物的预后等都是需要解决的其他问题。我们报告了一例32岁肾移植受者发生的伴有肺部受累的败血症性类鼻疽病,该病导致了急性移植物功能障碍。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f4f/5015521/b77a306c7789/IJN-26-379-g001.jpg

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