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对70岁以上患者进行减肥手术并随访18个月后的结果比较。

A comparison of outcomes of bariatric surgery in patient greater than 70 with 18 month of follow up.

作者信息

Zaveri Hinali, Surve Amit, Cottam Daniel, Summerhays Christina, Cottam Austin, Richards Christina, Belnap LeGrand, Medlin Walter

机构信息

Bariatric Medicine Institute, 1046 East 100 South, Salt Lake City, UT 84102 USA.

出版信息

Springerplus. 2016 Oct 7;5(1):1740. doi: 10.1186/s40064-016-3392-x. eCollection 2016.

Abstract

BACKGROUND

There is a scarcity of data available to determine the safety and effectiveness of bariatric surgery in the elderly population. Additionally, there are no studies showing the effect of the single anastomosis duodenal switch (SADS) has on the elderly obese, in comparison with other more popular procedures. Here we compare laparoscopic gastric band surgery (LAGB), Laparoscopic Roux-en-Y gastric bypass surgery (LRYGB), and the SADS to analyze the weight loss, perioperative and postoperative morbidity in the patients >70 years of age at a single US center.

METHODS

A retrospective analysis was performed on 53 consecutive patients ≥70 years old who underwent weight loss surgery from 2009 to 2015.Weight loss in terms of the percentage excess body mass index lost (%EBMIL), percentage excess weight lost (%EWL) and body mass index (BMI) points lost, resolution of comorbidities, length of stay, early (30-day) and late complication rates were compared using descriptive statistics and non-linear regression analysis.

RESULTS

Of 53 patients, 24 underwent LAGB, 14 underwent LRYGB and 15 underwent SADS. The average patient age was 72.7 ± 2.5 years (range, 70-81.4) and 66 % were females. There was no statistical difference in the demographic data between three groups except for age and sleep apnea. There were no operative or early deaths. There were differences in complication rates between the surgical arms; however, with our small data set statistical significance was not achieved. There was 1 patient who lost to follow up in SADS group. Follow up time period was 18 months.  % EBMIL and BMI reduction showed a statistically significant difference between the procedures, where the SADS had the highest loss of  %EBMIL and BMI points. Comorbidities prevalence decreased post-operatively with SADS having higher percentage of patients who had resolution of their comorbidities.

CONCLUSION

Each of the three procedures can be performed on patients older than 70 with low morbidity rate. However, when the focus is weight loss alone, the SADS procedure is the most effective of the three procedures in regards to weight loss in the short term for patients older than 70. The SADS is as safe as RYGB but LAGB with all its limitations is still the safest bariatric procedure.

摘要

背景

目前缺乏足够数据来确定减重手术在老年人群中的安全性和有效性。此外,尚无研究表明单吻合口十二指肠转位术(SADS)与其他更常用的手术相比,对老年肥胖患者的影响如何。在此,我们在美国的一家中心比较腹腔镜胃束带手术(LAGB)、腹腔镜Roux-en-Y胃旁路手术(LRYGB)和SADS,以分析70岁以上患者的体重减轻情况、围手术期和术后发病率。

方法

对2009年至2015年间连续接受减重手术的53例70岁及以上患者进行回顾性分析。使用描述性统计和非线性回归分析比较体重减轻情况,以超出体重指数丢失百分比(%EBMIL)、超出体重丢失百分比(%EWL)和体重指数(BMI)降低点数衡量,比较合并症的缓解情况、住院时间、早期(30天)和晚期并发症发生率。

结果

53例患者中,24例行LAGB,14例行LRYGB,15例行SADS。患者平均年龄为72.7±2.5岁(范围70 - 81.4岁),66%为女性。除年龄和睡眠呼吸暂停外,三组患者的人口统计学数据无统计学差异。无手术死亡或早期死亡。不同手术方式的并发症发生率存在差异;然而,由于我们的数据量较小,未达到统计学显著性。SADS组有1例患者失访。随访时间为18个月。%EBMIL和BMI降低在不同手术方式之间显示出统计学显著差异,其中SADS的%EBMIL和BMI降低幅度最大。术后合并症患病率降低,SADS组合并症缓解的患者比例更高。

结论

三种手术均可在70岁以上患者中进行,发病率较低。然而,若仅关注体重减轻,对于70岁以上患者,短期内SADS手术在减重方面是三种手术中最有效的。SADS与RYGB一样安全,但LAGB尽管有其局限性,仍是最安全的减重手术。

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