O'Mara Daniel M, DiCamillo Paul A, Gilson Wesley D, Herzka Daniel A, Wacker Frank K, Lewin Jonathan S, Weiss Clifford R
Department of Radiology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Vascular and Interventional Radiology, Department of Radiology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
J Magn Reson Imaging. 2017 Apr;45(4):1154-1162. doi: 10.1002/jmri.25502. Epub 2016 Oct 31.
To demonstrate the feasibility, safety, and effectiveness of image-guided sclerotherapy of low-flow vascular malformations using a 1.5 Tesla (T) MR scanner with real-time imaging capability and in-suite fluoroscopy.
Thirty-three procedures were performed with real-time 1.5T MR-guidance on 22 patients with a vascular malformation in the neck (n = 2), chest (n = 6), abdomen and pelvis (n = 15), and extremities (n = 11). Quantitative analysis was performed for changes in (a) planning time, (b) targeting time (interval between needle skin puncture and lesion access), (c) intervention time (interval between needle skin puncture and needle removal), and (d) total procedure time. Qualitative analysis was performed for (a) success of therapy and (b) occurrence of complications.
Technical success was achieved in 29 of 33 procedures. The average planning time did not significantly change between the first seven procedures and the last seven procedures (P = 0.447). The average targeting time decreased by 0:24:45 (hours:minutes:seconds) (P = 0.043), the average intervention time decreased by 0:26:58 (P = 0.022), and the average procedure time decreased by 0:28:41 (P = 0.046) when comparing the first seven procedures and the last seven procedures. Overall, there was an improvement in the patients' predominant symptoms following 82% of procedures, including a significant decrease in average pain following therapy (P < 0.001). There was a minor complication rate of 3% with no major complications.
MR-guided percutaneous sclerotherapy seems to be a safe, effective, and versatile technique for treating low-flow vascular malformations.
3 J. Magn. Reson. Imaging 2017;45:1154-1162.
证明使用具有实时成像能力和术中透视功能的1.5特斯拉(T)磁共振扫描仪对低流量血管畸形进行图像引导硬化治疗的可行性、安全性和有效性。
对22例患有颈部(n = 2)、胸部(n = 6)、腹部和骨盆(n = 15)以及四肢(n = 11)血管畸形的患者进行了33次实时1.5T磁共振引导下的手术。对以下方面的变化进行了定量分析:(a)规划时间,(b)靶向时间(从针刺皮肤到进入病变的间隔时间),(c)干预时间(从针刺皮肤到拔针的间隔时间),以及(d)总手术时间。对以下方面进行了定性分析:(a)治疗成功率,以及(b)并发症的发生情况。
33例手术中有29例取得技术成功。前七例手术和后七例手术之间的平均规划时间没有显著变化(P = 0.447)。与前七例手术相比,后七例手术的平均靶向时间减少了0:24:45(小时:分钟:秒)(P = 0.043),平均干预时间减少了0:26:58(P = 0.022),平均手术时间减少了0:28:41(P = 0.046)。总体而言,82%的手术后患者的主要症状有所改善,包括治疗后平均疼痛显著减轻(P < 0.001)。轻微并发症发生率为3%,无严重并发症。
磁共振引导下经皮硬化治疗似乎是一种安全、有效且通用的治疗低流量血管畸形的技术。
3 J. Magn. Reson. Imaging 2017;45:1154 - 1162。