Carlos Camila, Pereira Letícia Bianca, Ottoboni Laura Maria Mariscal
Department of Bacteriology, University of Wisconsin-Madison, Madison, WI, 53703, USA.
Center for Molecular Biology and Genetic Engineering (CBMEG), State University of Campinas (UNICAMP), C. P. 6010, Campinas, SP, 13083-875, Brazil.
Curr Genet. 2017 Jun;63(3):509-518. doi: 10.1007/s00294-016-0658-3. Epub 2016 Oct 31.
One of the main goals of coral microbiology is to understand the ways in which coral-bacteria associations are established and maintained. This work describes the sequencing of the genome of Paracoccus sp. SM22M-07 isolated from the mucus of the endemic Brazilian coral species Mussismilia hispida. Comparative analysis was used to identify unique genomic features of SM22M-07 that might be involved in its adaptation to the marine ecosystem and the nutrient-rich environment provided by coral mucus, as well as in the establishment and strengthening of the interaction with the host. These features included genes related to the type IV protein secretion system, erythritol catabolism, and succinoglycan biosynthesis. We experimentally confirmed the production of succinoglycan by Paracoccus sp. SM22M-07 and we hypothesize that it may be involved in the association of the bacterium with coral surfaces.
珊瑚微生物学的主要目标之一是了解珊瑚与细菌的共生关系是如何建立和维持的。这项工作描述了从巴西特有珊瑚物种希氏缪氏珊瑚（Mussismilia hispida）的黏液中分离出的嗜甲基球菌属（Paracoccus sp.）SM22M - 07的基因组测序。通过比较分析来确定SM22M - 07的独特基因组特征，这些特征可能涉及其对海洋生态系统和珊瑚黏液提供的营养丰富环境的适应，以及与宿主相互作用的建立和加强。这些特征包括与IV型蛋白质分泌系统、赤藓糖醇分解代谢和琥珀聚糖生物合成相关的基因。我们通过实验证实了嗜甲基球菌属SM22M - 07能产生琥珀聚糖，并推测它可能参与了该细菌与珊瑚表面的结合。
