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用于治疗高血压的营养补充剂:临床医生实用指南

Nutritional Supplements for the Treatment of Hypertension: A Practical Guide for Clinicians.

作者信息

Turner Jeffrey M, Spatz Erica S

机构信息

Department of Internal Medicine, Section of Nephrology, Yale University School of Medicine, BB114, 330 Cedar Street, New Haven, CT, 06520, USA.

Department of Internal Medicine, Section of Cardiovascular Medicine, Yale University School of Medicine, New Haven, CT, USA.

出版信息

Curr Cardiol Rep. 2016 Dec;18(12):126. doi: 10.1007/s11886-016-0806-x.

DOI:10.1007/s11886-016-0806-x
PMID:27796863
Abstract

Nutraceuticals are dietary components with pharmacologic properties that can be used to treat various disease states. There is growing interest among patients in the use of nutraceuticals for the management of hypertension; as such, it is important that clinicians are prepared to engage in meaningful discussions with their patients about these substances. Flavonoids, beetroot, garlic, and unsaturated fats have garnered significant attention for their blood pressure lowering properties. We review the clinical evidence and reported mechanisms of action for these substances in an attempt to offer a practical guide for clinicians to engage with patients who are highly motivated to seek out nutraceutical therapies to manage their hypertension.

摘要

营养保健品是具有药理特性的膳食成分,可用于治疗各种疾病状态。患者对使用营养保健品来管理高血压的兴趣日益浓厚;因此,临床医生准备好与患者就这些物质进行有意义的讨论非常重要。黄酮类化合物、甜菜根、大蒜和不饱和脂肪因其降血压特性而备受关注。我们回顾了这些物质的临床证据和报道的作用机制,试图为临床医生提供一份实用指南,以便与积极寻求营养保健品疗法来管理高血压的患者进行沟通。

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Nutritional Supplements for the Treatment of Hypertension: A Practical Guide for Clinicians.用于治疗高血压的营养补充剂:临床医生实用指南
Curr Cardiol Rep. 2016 Dec;18(12):126. doi: 10.1007/s11886-016-0806-x.
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本文引用的文献

1
Nutraceuticals for blood pressure control.用于控制血压的营养保健品。
Ann Med. 2015;47(6):447-56. doi: 10.3109/07853890.2015.1078905. Epub 2015 Sep 11.
2
Nutraceuticals and Blood Pressure Control: Results from Clinical Trials and Meta-Analyses.营养保健品与血压控制:临床试验及荟萃分析结果
High Blood Press Cardiovasc Prev. 2015 Sep;22(3):203-13. doi: 10.1007/s40292-015-0081-8. Epub 2015 Mar 19.
3
Dietary nitrate provides sustained blood pressure lowering in hypertensive patients: a randomized, phase 2, double-blind, placebo-controlled study.
铬补充剂对血压的影响:随机对照试验的系统评价和剂量反应荟萃分析。
High Blood Press Cardiovasc Prev. 2021 Jul;28(4):333-342. doi: 10.1007/s40292-021-00456-8. Epub 2021 Jun 3.
4
Effects of Lactotripeptide Supplementation on Tele-Monitored Home Blood Pressure and on Vascular and Renal Function in Prehypertension - Randomized, Double-Blind, Placebo-Controlled, Cross-Over Study.补充乳三肽对高血压前期远程监测家庭血压及血管和肾功能的影响——随机、双盲、安慰剂对照、交叉研究
Circ Rep. 2019 Oct 2;1(10):438-444. doi: 10.1253/circrep.CR-19-0061.
膳食硝酸盐可使高血压患者血压持续降低:一项随机、2期、双盲、安慰剂对照研究。
Hypertension. 2015 Feb;65(2):320-7. doi: 10.1161/HYPERTENSIONAHA.114.04675. Epub 2014 Nov 24.
4
A systematic review and metaanalysis on the effects of garlic preparations on blood pressure in individuals with hypertension.一项关于大蒜制剂对高血压患者血压影响的系统评价和荟萃分析。
Am J Hypertens. 2015 Mar;28(3):414-23. doi: 10.1093/ajh/hpu165. Epub 2014 Sep 18.
5
Mediterranean diet reduces 24-hour ambulatory blood pressure, blood glucose, and lipids: one-year randomized, clinical trial.地中海饮食可降低 24 小时动态血压、血糖和血脂:为期一年的随机临床试验。
Hypertension. 2014 Jul;64(1):69-76. doi: 10.1161/HYPERTENSIONAHA.113.03353. Epub 2014 May 5.
6
Long-chain omega-3 fatty acids eicosapentaenoic acid and docosahexaenoic acid and blood pressure: a meta-analysis of randomized controlled trials.长链ω-3脂肪酸二十碳五烯酸和二十二碳六烯酸与血压:随机对照试验的荟萃分析
Am J Hypertens. 2014 Jul;27(7):885-96. doi: 10.1093/ajh/hpu024. Epub 2014 Mar 6.
7
The role of nutrition and nutraceutical supplements in the treatment of hypertension.营养与营养保健品在高血压治疗中的作用。
World J Cardiol. 2014 Feb 26;6(2):38-66. doi: 10.4330/wjc.v6.i2.38.
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A single dose of beetroot juice enhances cycling performance in simulated altitude.一份研究指出,单次摄入甜菜根汁可提升模拟高海拔环境下的自行车骑行表现。
Med Sci Sports Exerc. 2014 Jan;46(1):143-50. doi: 10.1249/MSS.0b013e3182a1dc51.
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Inorganic nitrate and beetroot juice supplementation reduces blood pressure in adults: a systematic review and meta-analysis.无机硝酸盐和甜菜根汁补充剂可降低成年人的血压:系统评价和荟萃分析。
J Nutr. 2013 Jun;143(6):818-26. doi: 10.3945/jn.112.170233. Epub 2013 Apr 17.
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Enhanced vasodilator activity of nitrite in hypertension: critical role for erythrocytic xanthine oxidoreductase and translational potential.亚硝酸盐在高血压中的血管舒张活性增强:红细胞黄嘌呤氧化还原酶的关键作用和转化潜力。
Hypertension. 2013 May;61(5):1091-102. doi: 10.1161/HYPERTENSIONAHA.111.00933. Epub 2013 Apr 15.