Master Samip, Patel Abhishek, Mills Glenn, Mansour Richard
Department of Hematology and Oncology at the Louisiana State Univeristy Health Sciences Center in Shreveport, LA.
J La State Med Soc. 2016 Sep-Oct;168(5):152-155. Epub 2016 Nov 15.
Sickle Cell Disease (SCD) affects approximately 100,000 Americans and due to lack of an organized treatment approach, patients with SCD pose a high economic burden on medical services. The patients with SCD have chronic bone damage from bone marrow infraction and vaso-occulsive events. These bone damages lead to chronic pain in patients with SCD. The inadwquate treatment of chronic pain in adult patients with SCD can lead to pseudo-addictive behavior and also affect their psycho-social life. There are certain barriers to adequate pain management in adult patients with SCD, namely, limited knowledge among the clinicians, inadequate assessment, concerns about addiction, and biases against opioid use. Here by presenting radiographs of patients with adult SCD, we would like to provide objective evidence for the pathologic basis of severe chronic pain in adult patients with SCD.
镰状细胞病（SCD）影响着约10万名美国人，由于缺乏有组织的治疗方法，SCD患者给医疗服务带来了高昂的经济负担。SCD患者因骨髓梗死和血管阻塞事件而存在慢性骨损伤。这些骨损伤导致SCD患者出现慢性疼痛。成年SCD患者慢性疼痛治疗不足会导致假性成瘾行为，还会影响他们的心理社会生活。成年SCD患者充分疼痛管理存在一定障碍，即临床医生知识有限、评估不足、对成瘾的担忧以及对使用阿片类药物的偏见。在此，通过展示成年SCD患者的X光片，我们希望为成年SCD患者严重慢性疼痛的病理基础提供客观证据。
