Visciani A, Savoiardo M, Balestrini M R, Solero C L
Department of Neuroradiology, Istituto Neurologico, C. Besta, Milano, Italy.
Neuroradiology. 1989;31(3):273-5. doi: 10.1007/BF00344358.
An 11-year-old boy, treated for acute lymphatic leukemia at the age of 2 with intrathecal injections of Methotrexate, presented with a two year history of pain and signs of lumbo-sacral lesion. MRI, myelography and myelo-CT demonstrated an intradural L4-L5 epidermoid tumor which was removed. Iatrogenic implantation of epithelial cells at the age of two with lumbar punctures is most likely. Decline in incidence of lumbar iatrogenic epidermoid cysts, now an exceedingly rare event, is probably related to improved needles for lumbar punctures.
一名11岁男孩,2岁时接受鞘内注射甲氨蝶呤治疗急性淋巴细胞白血病,现出现两年的腰腿痛病史及腰骶部病变体征。磁共振成像(MRI)、脊髓造影和脊髓CT显示硬膜内L4-L5节段表皮样囊肿,遂将其切除。最有可能的原因是2岁时腰椎穿刺导致上皮细胞医源性植入。目前腰椎医源性表皮样囊肿的发病率下降,这一情况极为罕见,可能与腰椎穿刺针的改进有关。