Yuda Kentaro, Ishida Atsuyuki, Yuda Kenji
*Department of Ophthalmology, Kikuna Yuda Eye Clinic, Yokohama, Japan; †Department of Ophthalmology, Yokohama City University School of Medicine, Yokohama, Japan; and ‡Department of Ophthalmology, Yokohama Minami Kyosai Hospital, Yokohama, Japan.
Retina. 2017 Jul;37(7):1393-1399. doi: 10.1097/IAE.0000000000001375.
To compare the retinal blood flow velocity using laser speckle flowgraphy (LSFG) and a retinal function imager (RFI) in healthy Japanese subjects.
This study included a total of 15 eyes of 15 healthy Japanese subjects (mean age, 41.7 ± 17.0 years). The retinal blood flow velocities were separately measured in arteries and veins around the optic disc using LSFG and an RFI. Linear regression analyses were used to analyze possible correlations of retinal blood flow velocities between the devices.
The average blood flow velocities using LSFG as the mean blur rate were 18.6 ± 4.8 in arteries and 18.3 ± 5.5 in veins. The average blood flow velocities using the RFI were 3.4 ± 1.1 mm/second in arteries and 2.9 ± 0.9 mm/second in veins. Although retinal blood flow velocities in arteries and veins using LSFG were nearly the same, there were statistical differences in retinal blood flow velocities between arteries and veins using the RFI (P = 0.701 using LSFG, P = 0.041 using the RFI). Significant correlations were found between LSFG and the RFI in arteries and veins (all, P < 0.001).
There were strong positive correlations in retinal blood flow velocities between LSFG and the RFI in healthy subjects.
比较激光散斑血流图（LSFG）和视网膜功能成像仪（RFI）在健康日本受试者中测量的视网膜血流速度。
本研究共纳入15名健康日本受试者的15只眼睛（平均年龄41.7±17.0岁）。使用LSFG和RFI分别测量视盘周围动脉和静脉的视网膜血流速度。采用线性回归分析来分析两种设备测量的视网膜血流速度之间可能存在的相关性。
以平均模糊率表示，使用LSFG测量的动脉平均血流速度为18.6±4.8，静脉平均血流速度为18.3±5.5。使用RFI测量的动脉平均血流速度为3.4±1.1毫米/秒，静脉平均血流速度为2.9±0.9毫米/秒。虽然使用LSFG测量的动脉和静脉视网膜血流速度几乎相同，但使用RFI测量时，动脉和静脉的视网膜血流速度存在统计学差异（使用LSFG时P = 0.701，使用RFI时P = 0.041）。在动脉和静脉中，LSFG与RFI之间均存在显著相关性（均P < 0.001）。
在健康受试者中，LSFG和RFI测量的视网膜血流速度之间存在强正相关。
