Sborgia Luigi, Recchimurzo Nicola, Niro Alfredo, Sborgia Giancarlo, Furino Claudio, Boscia Francesco, Alessio Giovanni
Department of Medical Science, Neuroscience and Sense Organs, University of Bari, Bari, Italy.
Eye Clinic, University of Sassari, Sassari, Italy.
Retin Cases Brief Rep. 2018;12(3):207-211. doi: 10.1097/ICB.0000000000000465.
To report optical coherence tomography and microperimetric correlated changes in a case of bilateral foveal schisis in progressive X-linked retinoschisis (XLRS) treated with vitrectomy, inner limiting membrane (ILM) peeling, and air tamponade.
One case report.
An 18-year-old boy with bilateral foveal schisis in progressive XLRS underwent vitrectomy, ILM peeling and air tamponade in both eyes. At baseline and follow-up (1 month in right eye, 6 months in left eye), visual acuity test, optical coherence tomography, retinal sensitivity map, and fixation stability study were performed. At the end of follow-up, in both eyes, the largest foveal schisis cavities resolved, central macular thickness and volume on optical coherence tomography decreased, and visual acuity improved. In right eye, the mean retinal sensitivity is worsened after 1 month from surgery and conversely central macular sensitivity improved; in left eye, retinal sensitivity improved overall after 6 months from surgery; fixation became more stable in both eyes. There were no adverse events.
Retinal sensitivity and fixation behavior analysis could be a complementary tool respect in addition to visual acuity test and optical coherence tomography to investigate the efficacy of vitrectomy with ILM in progressive X-linked foveal schisis to prevent functional impairment before it happens.
报告在一例进行性X连锁视网膜劈裂症(XLRS)双侧黄斑劈裂患者中,接受玻璃体切除术、内界膜(ILM)剥除术及空气填塞治疗后的光学相干断层扫描(OCT)和微视野检查相关变化。
病例报告。
一名患有进行性XLRS双侧黄斑劈裂的18岁男孩双眼均接受了玻璃体切除术、ILM剥除术及空气填塞。在基线及随访时(右眼1个月,左眼6个月),进行了视力测试、OCT、视网膜敏感度图及注视稳定性研究。随访结束时,双眼最大黄斑劈裂腔均消失,OCT上的中心黄斑厚度及体积减小,视力提高。右眼术后1个月平均视网膜敏感度变差,而中心黄斑敏感度提高;左眼术后6个月总体视网膜敏感度提高;双眼注视均变得更稳定。无不良事件发生。
除视力测试和OCT外,视网膜敏感度及注视行为分析可能是一种辅助工具,用于研究ILM玻璃体切除术对进行性X连锁黄斑劈裂的疗效,以在功能损害发生前预防其发生。