Kitagawa Hiroyuki, Namikawa Tsutomu, Munekage Masaya, Fujisawa Kazune, Munekage Eri, Kawanishi Yasuhiro, Kobayashi Michiya, Hanazaki Kazuhiro
Department of Surgery, Kochi Medical School, Nankoku, Japan.
Department of Surgery, Kochi Medical School, Nankoku, Japan
Anticancer Res. 2016 Oct;36(10):5409-5412. doi: 10.21873/anticanres.11117.
To investigate the factors associated with weight loss (WL) after esophagectomy for esophageal cancer.
We retrospectively reviewed 136 patients who underwent esophagectomy for esophageal cancer. Preoperative characteristics, surgical methods, postoperative outcomes and weight changes at 6 months after surgery were analyzed.
Seventy-eight patients had more than 10% WL compared to their weight at surgery. On univariate analysis, higher body mass index [(BMI): ≥20.8; p=0.012] and shorter length of hospitalization [(LOH); p=0.041] demonstrated an association with more than 10% WL. On multivariate analysis, higher BMI [odds ratio (OR)=2.821; 95% confidence interval (CI)=1.238-6.426; p=0.014] and shorter LOH (OR=2.953; 95% CI=1.009-8.646; p=0.048) were independently associated with more than 10% WL.
Higher BMI and shorter LOH were unfavorable risk factors for WL after esophagectomy for esophageal cancer.
探讨食管癌切除术后体重减轻（WL）的相关因素。
我们回顾性分析了136例行食管癌切除术的患者。分析了患者的术前特征、手术方式、术后结局及术后6个月的体重变化。
78例患者术后体重较手术时减轻超过10%。单因素分析显示，较高的体重指数[（BMI）：≥20.8；p=0.012]和较短的住院时间[（LOH）；p=0.041]与超过10%的体重减轻相关。多因素分析显示，较高的BMI[比值比（OR）=2.821；95%置信区间（CI）=1.238 - 6.426；p=0.014]和较短的LOH（OR=2.953；95%CI=1.009 - 8.646；p=0.048）与超过10%的体重减轻独立相关。
较高的BMI和较短的LOH是食管癌切除术后体重减轻的不利危险因素。
