Han Jin-Sol, Kim Se-Hoon, Jin Sung-Won, Lee Seung-Hwan, Kim Bum-Joon, Kim Sang-Dae, Lim Dong-Jun
Department of Neurosurgery, Korea University Ansan Hospital, Korea University College of Medicine, Ansan, Korea.
Korean J Spine. 2016 Sep;13(3):129-133. doi: 10.14245/kjs.2016.13.3.129. Epub 2016 Sep 30.
Surgical site infection (SSI) is the one of the most frequent complications in hospitalized patients, and it extends hospital stays and causes extra morbidities. To reduce SSI after spine surgery, we applied the gentamicin-impregnated collagen sponge (Collatamp G) during the operation and analyzed the results retrospectively.
Between October 2012 and December 2015, we collected data who applied the Collatamp G in spine surgery at a single institution. Demographic data of patients and another possible risk factors of SSI were also included, and we assessed the correlation between the risk factors and the developing of SSI by reviewing electronic medical records retrospectively.
Three percent of all patients (10 of 280) developed the SSI and only 0.8% of patients who applied Collatamp G developed SSI (1 of 119). Otherwise, 5% of patients who did not apply Collatamp G developed SSI (9 of 161) (p=0.034). We also analyzed the correlation between SSI and other potential risk factors but nothings showed statistical correlation with SSI.
In this study, there were statistically significant results that SSI rate was decreased in the group of patients using Collatamp G in spine surgery generally. However, further studies are required to resolve some limitations in the future.
手术部位感染（SSI）是住院患者最常见的并发症之一，它会延长住院时间并导致额外的发病情况。为了减少脊柱手术后的SSI，我们在手术中应用了庆大霉素浸渍胶原海绵（Collatamp G）并进行回顾性结果分析。
在2012年10月至2015年12月期间，我们收集了在单一机构进行脊柱手术时应用Collatamp G的患者数据。还纳入了患者的人口统计学数据以及SSI的其他可能风险因素，我们通过回顾电子病历对风险因素与SSI发生之间的相关性进行了评估。
所有患者中有3%（280例中的10例）发生了SSI，而应用Collatamp G的患者中只有0.8%发生了SSI（119例中的1例）。否则，未应用Collatamp G的患者中有5%发生了SSI（161例中的9例）（p = 0.034）。我们还分析了SSI与其他潜在风险因素之间的相关性，但未发现任何因素与SSI有统计学相关性。
在本研究中，有统计学显著结果表明脊柱手术中使用Collatamp G的患者组SSI发生率总体上有所降低。然而，未来需要进一步研究以解决一些局限性。
