Kim Ki-Wan, Oh Young-Min, Eun Jong-Pil
Department of Neurosurgery, Chonbuk National University Medical School, Jeonju, Korea.
Korean J Spine. 2016 Sep;13(3):139-143. doi: 10.14245/kjs.2016.13.3.139. Epub 2016 Sep 30.
There are also few studies demonstrating the relationship between ossification of nuchal ligament (ONL) and ossification of posterior longitudinal ligament (OPLL). We compared the prevalence, location, and type of OPLL between patients with ONL and matched patients without ONL.We also compared the bone mineral densities (BMDs) between the 2 groups.
total of 124 cervical ONL patients were enrolled in this study. The control group of 124 patients was matched with 124 patients with ONL by age and sex on a 1:1 basis to minimize confounding factors. We reviewed the prevalence, location, and type of OPLL in both groups.
The prevalence of OPLL was almost 2.5 times greater in patients with ONL than those without ONL. The mean value of BMD in patients with ONL was greater at the lumbar spine (L1-L4) than in patients without ONL. The mean T score of the lumbar spine was 0.25±1.68 in the patients with ONL and -0.73±1.64 in the patients without ONL.
The prevalence of OPLL in patients with ONL was significantly higher than in patients without ONL. Because ONL is innocuous and may be seen more readily than OPLL on simple cervical radiographs, clinicians should consider the possibility of coexisting OPLL when ONL, especially extensive ONL, is detected in patients with neck pain, radiculopathy, or myelopathy, to facilitate proper treatment.
很少有研究证实项韧带骨化（ONL）与后纵韧带骨化（OPLL）之间的关系。我们比较了ONL患者与配对的无ONL患者之间OPLL的患病率、位置和类型。我们还比较了两组之间的骨密度（BMD）。
本研究共纳入124例颈椎ONL患者。124例患者的对照组按年龄和性别1:1与124例ONL患者配对，以尽量减少混杂因素。我们回顾了两组中OPLL的患病率、位置和类型。
ONL患者中OPLL的患病率几乎是无ONL患者的2.5倍。ONL患者腰椎（L1-L4）的BMD平均值高于无ONL患者。ONL患者腰椎的平均T值为0.25±1.68，无ONL患者为-0.73±1.64。
ONL患者中OPLL的患病率显著高于无ONL患者。由于ONL无害，且在简单的颈椎X线片上可能比OPLL更容易看到，因此当在颈痛、神经根病或脊髓病患者中检测到ONL，尤其是广泛的ONL时，临床医生应考虑并存OPLL的可能性，以便进行适当治疗。
