Prevalence of Virulence-Related Determinants in Clinical Isolates of .

BACKGROUND

, a member of the human flora, is recognized as an opportunistic pathogen and cause of nosocomial infections. surface components are able to establish bacteria on the host surface, and cause infection.

OBJECTIVES

The frequency of , , , and in clinical isolates of were investigated in this study.

MATERIALS AND METHODS

Fifty-nine isolates were collected from blood (50), wound (1), urine (4) and tracheal (4) samples (Tehran, Iran). isolates were identified with conventional bacteriological tests. Virulence-associated genes were detected by specific polymerase chain reactions (PCRs).

RESULTS

Of the 59 , was found in 89.8%, while and were observed in 64.4% and 15.3% of the samples, respectively. Coexistence of and was found in 32 isolates, while coexistence of and was observed in five isolates. Two isolates were negative for the investigated genes.

CONCLUSIONS

Prevalence of and was significantly different from similar studies, yet frequency of was in accordance with other studies. Prevalence of and was not significantly different from some studies while a significant difference was observed when results were compared with some other studies.