An Investigation of Antibacterial Resistance Patterns Among and Isolates Collected from Intensive Care Units of a University-Affiliated Hospital in Ahvaz, Iran.

BACKGROUND

In recent decades, multidrug-resistant non-fermenting Gram-negative pathogens, particularly and , have been recognized as a major cause of healthcare-associated and nosocomial infections and outbreaks.

OBJECTIVES

The aim of this study was to determine the prevalence and pattern of antibiotic resistance in and isolates collected from intensive care units (ICUs).

METHODS

One hundred fifty-five clinical isolates, including 80 (51.6%) isolates of and 75 (48.4%) isolates of , from hospitalized patients in the ICUs of a teaching hospital in Ahvaz, Iran, were collected from January 1 to December 30, 2013. The organisms were identified with conventional bacteriological methods, and antimicrobial susceptibility testing was performed on all isolates in accordance with clinical laboratory and standards institute (CLSI) guidelines.

RESULTS

The maximum resistance rates among isolates were observed for ciprofloxacin and trimethoprim-sulfamethoxazole (96.9% and 95.2%, respectively). For isolates, the maximum resistance rates were reported for ceftriaxone and trimethoprim-sulfamethoxazole (97.2% and 92.4%, respectively).

CONCLUSIONS

The majority of and isolates were found to be resistant to commonly recommended antibiotics. Therefore, surveillance of antibiotic consumption and proper antibiotic administration guidelines are essential for preventing major outbreaks in the future.