National Creative Research Initiative Center for Catalytic Organic Reactions, Department of Chemistry, Kangwon National University , Chuncheon 24341, Republic of Korea.
J Org Chem. 2016 Dec 2;81(23):11706-11715. doi: 10.1021/acs.joc.6b02140. Epub 2016 Nov 10.
Rhodium-catalyzed denitrogenative cyclization of (E)-ethyl 2-(1-alkyl and arylsulfonyl-1H-1,2,3-triazol-4-yl)-3-aryl acrylate generated from (E)-ethyl 2-benzylidenebut-3-ynoates and N-sulfonyl azides in the presence of a copper catalyst was developed for the synthesis of a large number of functionalized benzofulvenes. Moreover, the synthesis of benzofulvenes was demonstrated as a one-pot method through tandem copper-catalyzed [3 + 2] cycloaddition and rhodium-catalyzed denitrogenative cyclization from (E)-ethyl 2-benzylidenebut-3-ynoates and N-sulfonyl azides.
铑催化的（E）-乙基 2-（1-烷基和芳基磺酰基-1H-1,2,3-三唑-4-基）-3-芳基丙烯酸酯的脱氮环化反应，由（E）-乙基 2-亚苄基丁-3-炔酸酯和 N-磺酰基叠氮化物在铜催化剂的存在下生成，用于合成大量功能化的苯并呋喃。此外，通过（E）-乙基 2-亚苄基丁-3-炔酸酯和 N-磺酰基叠氮化物的串联铜催化[3+2]环加成和铑催化的脱氮环化反应，证明了苯并呋喃的合成为一锅法。
