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论三维、几何精确且针对个体的有限元分析在评估体内软组织负荷中的重要性。

On the importance of 3D, geometrically accurate, and subject-specific finite element analysis for evaluation of in-vivo soft tissue loads.

作者信息

Moerman Kevin M, van Vijven Marc, Solis Leandro R, van Haaften Eline E, Loenen Arjan C Y, Mushahwar Vivian K, Oomens Cees W J

机构信息

a Media-Lab. , Centre for Extreme Bionics, Massachusetts Institute of Technology , Cambridge , MA , USA.

b Trinity Centre for Bioengineering , University of Dublin, Trinity College , Dublin , Ireland.

出版信息

Comput Methods Biomech Biomed Engin. 2017 Apr;20(5):483-491. doi: 10.1080/10255842.2016.1250259. Epub 2016 Nov 1.

DOI:10.1080/10255842.2016.1250259
PMID:27800698
Abstract

Pressure ulcers are a type of local soft tissue injury due to sustained mechanical loading and remain a common issue in patient care. People with spinal cord injury (SCI) are especially at risk of pressure ulcers due to impaired mobility and sensory perception. The development of load improving support structures relies on realistic tissue load evaluation e.g. using finite element analysis (FEA). FEA requires realistic subject-specific mechanical properties and geometries. This study focuses on the effect of geometry. MRI is used for the creation of geometrically accurate models of the human buttock for three able-bodied volunteers and three volunteers with SCI. The effect of geometry on observed internal tissue deformations for each subject is studied by comparing FEA findings for equivalent loading conditions. The large variations found between subjects confirms the importance of subject-specific FEA.

摘要

压疮是由于持续机械负荷导致的一种局部软组织损伤,在患者护理中仍然是一个常见问题。脊髓损伤(SCI)患者由于行动能力和感觉功能受损,尤其有发生压疮的风险。开发负荷改善支撑结构依赖于现实的组织负荷评估,例如使用有限元分析(FEA)。有限元分析需要现实的个体特异性力学性能和几何形状。本研究聚焦于几何形状的影响。对三名健全志愿者和三名脊髓损伤志愿者,使用磁共振成像(MRI)创建人体臀部几何精确模型。通过比较等效负荷条件下的有限元分析结果,研究几何形状对每个受试者观察到的内部组织变形的影响。受试者之间发现的巨大差异证实了个体特异性有限元分析的重要性。

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