Department of Biomedical Engineering and Computational Biomodeling (CoBi) Core, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio, United States of America.
PLoS One. 2022 Aug 15;17(8):e0272051. doi: 10.1371/journal.pone.0272051. eCollection 2022.
Capturing the surface mechanics of musculoskeletal extremities would enhance the realism of life-like mechanics imposed on the limbs within surgical simulations haptics. Other fields that rely on surface manipulation, such as garment or prosthetic design, would also benefit from characterization of tissue surface mechanics. Eight homogeneous tissue models were developed for the upper and lower legs and arms of two donors. Ultrasound indentation data was used to drive an inverse finite element analysis for individualized determination of region-specific material coefficients for the lumped tissue. A novel calibration strategy was implemented by using a ratio based adjustment of tissue properties from linear regression of model predicted and experimental responses. This strategy reduced requirement of simulations to an average of under four iterations. These free and open-source specimen-specific models can serve as templates for simulations focused on mechanical manipulations of limb surfaces.
捕获肌肉骨骼四肢的表面力学特性将增强手术模拟触觉中施加在四肢上的逼真机械力学效果。其他依赖于表面操作的领域，如服装或假肢设计，也将受益于组织表面力学特性的描述。为两位捐赠者的上下腿和手臂开发了 8 个同质组织模型。超声压痕数据用于驱动逆有限元分析，以针对特定区域的组织进行个体确定。通过使用基于线性回归模型预测和实验响应的组织特性比值调整来实现新的校准策略。这种策略将模拟的需求平均减少到不到四次迭代。这些免费且开源的特定于标本的模型可以作为模拟的模板，用于专注于肢体表面的机械操作。
