改善孕期药物治疗研发与测试的流程。
Improving the Pipeline for Developing and Testing Pharmacological Treatments in Pregnancy.
作者信息
Chappell Lucy C, David Anna L
机构信息
Women's Health Academic Centre, King's College London, London, United Kingdom.
Institute for Women's Health, University College London, London, United Kingdom.
出版信息
PLoS Med. 2016 Nov 1;13(11):e1002161. doi: 10.1371/journal.pmed.1002161. eCollection 2016 Nov.
Abstract
In a Perspective, Lucy Chappell and Anna David discuss ways to develop and test pharmacological treatments in pregnancy.
摘要
露西·查佩尔和安娜·大卫在一篇《观点》文章中讨论了开发和测试孕期药物治疗方法的途径。
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本文引用的文献
1
Pregnancy-Associated Changes in Pharmacokinetics: A Systematic Review.
PLoS Med. 2016 Nov 1;13(11):e1002160. doi: 10.1371/journal.pmed.1002160. eCollection 2016 Nov.
2
Paediatric Drug Development and Formulation Design-a European Perspective.
AAPS PharmSciTech. 2017 Feb;18(2):241-249. doi: 10.1208/s12249-016-0558-3. Epub 2016 Jun 7.
3
Preterm labor: current pharmacotherapy options for tocolysis.
Expert Opin Pharmacother. 2014 Apr;15(6):787-97. doi: 10.1517/14656566.2014.889684. Epub 2014 Feb 17.
4
The role of teratology information services in screening for teratogenic exposures: challenges and opportunities.
Am J Med Genet C Semin Med Genet. 2011 Aug 15;157C(3):195-200. doi: 10.1002/ajmg.c.30303. Epub 2011 Jul 11.
5
The long-term effects of in utero exposures--the DES story.
N Engl J Med. 2011 Jun 2;364(22):2083-4. doi: 10.1056/NEJMp1104409. Epub 2011 Apr 20.
6
Off-label prescribing during pregnancy in the UK: an analysis of 18,000 prescriptions in Liverpool Women's Hospital.
Int J Pharm Pract. 2010 Aug;18(4):226-9. doi: 10.1211/ijpp.18.04.0007.
7
Thalidomide induces limb defects by preventing angiogenic outgrowth during early limb formation.
Proc Natl Acad Sci U S A. 2009 May 26;106(21):8573-8. doi: 10.1073/pnas.0901505106. Epub 2009 May 11.
8
Market failure and the poverty of new drugs in maternal health.
PLoS Med. 2008 Jan 22;5(1):e22. doi: 10.1371/journal.pmed.0050022.
9
Prescription, over-the-counter, and herbal medicine use in a rural, obstetric population.
Am J Obstet Gynecol. 2003 Apr;188(4):1039-45. doi: 10.1067/mob.2003.223.
10
Fetal programming and adult health.
Public Health Nutr. 2001 Apr;4(2B):611-24. doi: 10.1079/phn2001145.
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