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不孕症女性亚临床生殖器结核的诊断与管理洞察

Insight into the diagnosis and management of subclinical genital tuberculosis in women with infertility.

作者信息

Mahajan Nalini, Naidu Padmaja, Kaur Simran Deep

机构信息

Department of Reproductive Medicine, Mother and Child Hospital, New Delhi, India; Milann Fertility Centre, New Delhi, India.

Milann Fertility Centre, New Delhi, India.

出版信息

J Hum Reprod Sci. 2016 Jul-Sep;9(3):135-144. doi: 10.4103/0974-1208.192043.

DOI:10.4103/0974-1208.192043
PMID:27803580
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5070394/
Abstract

Genital tuberculosis (GTB) is an important cause of infertility in India. Lack of an accurate diagnostic test has led to an indiscriminate use of antitubercular treatment in infertile women. Apart from concerns of drug toxicity, this may be a contributing factor in the increasing incidence of multidrug-resistant TB reported in India. We conducted a study to analyze whether a combination of tests could help improve diagnostic accuracy. An algorithm for the management of GTB in infertile women based on the use of multiple tests is presented.

摘要

生殖器结核（GTB）是印度不孕症的一个重要原因。缺乏准确的诊断测试导致在不孕女性中不加区分地使用抗结核治疗。除了对药物毒性的担忧外，这可能是印度报告的耐多药结核病发病率上升的一个促成因素。我们进行了一项研究，以分析联合检测是否有助于提高诊断准确性。本文提出了一种基于多种检测方法的不孕女性GTB管理算法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1587/5070394/feb9629a9600/JHRS-9-135-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1587/5070394/c4c1102b766f/JHRS-9-135-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1587/5070394/feb9629a9600/JHRS-9-135-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1587/5070394/c4c1102b766f/JHRS-9-135-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1587/5070394/feb9629a9600/JHRS-9-135-g002.jpg

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本文引用的文献

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Female genital tuberculosis--a diagnostic and therapeutic challenge.女性生殖器结核——诊断与治疗的挑战
Indian J Tuberc. 2014 Apr;61(2):98-102.
2
Latent tuberculosis infection: what we know about its genetic control?潜伏性结核感染：我们对其基因控制了解多少？
Tuberculosis (Edinb). 2014 Sep;94(5):462-8. doi: 10.1016/j.tube.2014.06.009. Epub 2014 Jul 2.
3
Genital tuberculosis: Comparative study of the diagnostic modalities.生殖器结核：诊断方法的比较研究
女性生殖器结核导致不孕及其对原发性和继发性不孕的影响：系统评价和荟萃分析。
Sultan Qaboos Univ Med J. 2022 Aug;22(3):314-324. doi: 10.18295/squmj.1.2022.003. Epub 2022 Aug 25.
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Recent Advances in Diagnosis and Management of Female Genital Tuberculosis.女性生殖器结核诊断与管理的最新进展
J Obstet Gynaecol India. 2021 Oct;71(5):476-487. doi: 10.1007/s13224-021-01523-9. Epub 2021 Aug 28.
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A Study on Diagnostic Evaluation of Two Different Rapid DNA Polymerase Chain Reaction Techniques Namely Gene Xpert Mycobacterium Tuberculosis/Rifampin (MTB/RIF) and Mycoreal Polymerase Chain Reaction in the Diagnosis of Endometrial Tuberculosis Considering Culture as Gold Standard.一项以培养为金标准，评估两种不同的快速DNA聚合酶链反应技术（即Gene Xpert结核分枝杆菌/利福平检测（MTB/RIF）和Mycoreal聚合酶链反应）在子宫内膜结核诊断中的研究。
J Hum Reprod Sci. 2020 Oct-Dec;13(4):290-295. doi: 10.4103/jhrs.JHRS_16_20. Epub 2020 Dec 28.
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Etiopathogenesis, Challenges and Remedies Associated With Female Genital Tuberculosis: Potential Role of Nuclear Receptors.与女性生殖器结核相关的病因发病机制、挑战和补救措施：核受体的潜在作用。
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Int J Reprod Biomed. 2019 Dec 30;17(12):929-934. doi: 10.18502/ijrm.v17i12.5799. eCollection 2019 Dec.
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