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不良童年经历与饮食障碍临床特征的关系。

Associations between adverse childhood experiences and clinical characteristics of eating disorders.

机构信息

Department of Psychiatric Emergency &Acute Care, Lapeyronie Hospital, CHRU Montpellier, Montpellier, France.

Inserm, U1061, University of Montpellier, Montpellier, France.

出版信息

Sci Rep. 2016 Nov 2;6:35761. doi: 10.1038/srep35761.

Abstract

Patients with eating disorders (EDs) frequently report a history of childhood trauma (CT). We investigated whether certain subtypes of CT are associated with more severe features of EDs, independently of psychiatric comorbidity, and whether they act additively. One hundred and ninety-two patients with DSM-V-defined EDs were consecutively recruited. Five clinical characteristics were assessed: restraint, eating, shape and weight concerns on the EDE-Q, and daily functioning. CT was assessed by the childhood traumatism questionnaire. The clinical features were associated with at least one CT subtype (emotional, sexual or physical abuse, emotional neglect). Multivariate analyses adjusted for lifetime comorbid psychiatric disorders revealed that emotional abuse independently predicted higher eating, shape and weight concerns and lower daily functioning, whereas sexual and physical abuse independently predicted higher eating concern. A dose-effect relationship characterised the number of CT subtypes and the severity of the clinical features, suggesting a consistent and partly independent association between CT and more severe clinical and functional characteristics in EDs. Emotional abuse seems to have the most specific impact on ED symptoms. Last, not all CT subtypes have the same impact but they do act additively.

摘要

患有饮食失调症(ED)的患者经常报告有儿童期创伤(CT)的病史。我们调查了某些特定类型的 CT 是否与 ED 的更严重特征有关,而与精神共病无关,以及它们是否具有相加作用。连续招募了 192 名符合 DSM-V 定义的 ED 患者。评估了 5 种临床特征:EDE-Q 中的克制、进食、体型和体重问题以及日常功能。使用儿童创伤问卷评估 CT。临床特征与至少一种 CT 亚型(情感、性或身体虐待、情感忽视)有关。调整了终生共病精神障碍的多变量分析表明,情感虐待独立预测了更高的进食、体型和体重问题以及更低的日常功能,而性和身体虐待独立预测了更高的进食问题。CT 亚型的数量和临床特征的严重程度之间存在剂量-效应关系,这表明 CT 与 ED 中更严重的临床和功能特征之间存在一致且部分独立的关联。情感虐待似乎对 ED 症状的影响最具特异性。最后,并非所有 CT 亚型都有相同的影响,但它们确实具有相加作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ebe5/5090200/4e2c6ea04107/srep35761-f1.jpg

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