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中央巨细胞肉芽肿康复的多学科方法:一份临床报告。

Multidisciplinary approach for the rehabilitation of central giant cell granuloma: a clinical report.

作者信息

Yuzbasioglu Emir, Alkan Alper, Ozer Mete, Bayram Mehmet

机构信息

Department of Prosthodontics, School of Dentistry, Istanbul Medipol University, Istanbul, Turkey.

出版信息

Niger J Clin Pract. 2014 Jul-Aug;17(4):528-33. doi: 10.4103/1119-3077.134060.

DOI:10.4103/1119-3077.134060
PMID:24909482
Abstract

The central giant cell granuloma (CGCG) is benign, nonodontogenic, and intraosseous lesion of the jaw. Aggressive subtypes of CGCG have a tendency to recur after excision and require wide resection that leads to major defects in the jaw. In this case report a patient who had severe mandibular bony deficiency as a result of excision of aggressive CGCG, orthodontic, and prosthetic treatment was described. The defect was reconstructed with iliac bone graft. Four years later vertical distraction osteogenesis was performed on the grafted mandible in order to obtain a satisfactory bony height of mandibular ridge. After healing period three endosseous dental implants were placed to grafted region. Because of pubertal growth stage, a hybrid removable denture was constructed. The construction of a hybrid removable denture markedly improved the patient's speech, mastication, and appearance. After pubertal growth stage, a fixed partial denture construction was planned and future parts of treatment procedures were described to the patient. Distraction osteogenesis and endosseous dental implants can be a good alternative method for the unsatisfactory reconstructions of mandibular deficiencies.

摘要

中央巨细胞肉芽肿(CGCG)是颌骨的一种良性、非牙源性的骨内病变。侵袭性亚型的CGCG在切除后有复发倾向,需要广泛切除,这会导致颌骨出现重大缺损。在本病例报告中,描述了一名因侵袭性CGCG切除、正畸和修复治疗导致严重下颌骨骨质缺损的患者。缺损采用髂骨移植进行重建。四年后,对移植的下颌骨进行垂直骨牵张成骨,以获得满意的下颌牙槽嵴骨高度。愈合期过后,在移植区域植入了三颗骨内牙种植体。由于处于青春期生长阶段,制作了一副混合可摘义齿。混合可摘义齿的制作显著改善了患者的语音、咀嚼和外观。青春期生长阶段过后,计划制作固定局部义齿,并向患者描述了未来的部分治疗程序。骨牵张成骨和骨内牙种植体对于下颌骨缺损的不满意重建可能是一种很好的替代方法。

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引用本文的文献

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Relevance and Timing of Implant-Driven Rehabilitation in Central Giant Cell Granuloma Cases-A Scoping Review.中央巨细胞肉芽肿病例中种植体驱动修复的相关性和时机——一项范围综述
Clin Exp Dent Res. 2025 Feb;11(1):e70085. doi: 10.1002/cre2.70085.
2
Systematic analysis on the efficacy of bone enhancement methods used for success in dental implants.用于牙种植成功的骨增强方法疗效的系统分析。
J Indian Prosthodont Soc. 2017 Jul-Sep;17(3):219-225. doi: 10.4103/jips.jips_19_17.
3
Combination therapies for the treatment of recurrent central giant cell lesion in the maxilla: a case report.
上颌骨复发性中央巨细胞病变的联合治疗:病例报告
J Med Case Rep. 2017 Mar 20;11(1):74. doi: 10.1186/s13256-016-1173-3.