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主动脉腔内球囊阻断复苏术:前景、实践与进展?

Resuscitative endovascular balloon occlusion of the aorta: promise, practice, and progress?

机构信息

aCentre for Trauma Sciences, Blizard Institute, Queen Mary University of London, London bNHS Lothian, Royal Infirmary of Edinburgh, Edinburgh, UK.

出版信息

Curr Opin Crit Care. 2016 Dec;22(6):563-571. doi: 10.1097/MCC.0000000000000367.

DOI:10.1097/MCC.0000000000000367
PMID:27805960
Abstract

PURPOSE OF REVIEW

Resuscitative endovascular balloon occlusion of the aorta (REBOA) is a minimally invasive damage control procedure for life-threatening abdominal or pelvic haemorrhage. The purpose of this review is to summarize the current understanding and experience with REBOA, outline potential future applications of this technology, and highlight priority areas for further research.

RECENT FINDINGS

REBOA is a feasible method of achieving temporary aortic occlusion and can be performed rapidly, with a high degree of success, in the emergency setting (including at the scene of injury) by appropriately trained clinicians. The procedure supports central perfusion, controls noncompressible haemorrhage, and may improve survival in certain profoundly shocked patient groups; but is also associated with significant risks, including ischaemic tissue damage and procedural complications. Evolutions of this strategy are being explored, with promising proof-of-concept studies in the fields of partial aortic occlusion and the combination of REBOA with extracorporeal support.

SUMMARY

Noncompressible torso haemorrhage is the leading cause of preventable trauma deaths. The majority of these deaths occur soon after injury, often before any opportunity for definitive haemorrhage control. For a meaningful reduction in trauma mortality, novel methods of rapid haemorrhage control are required.

摘要

目的综述

主动脉球囊阻断复苏术(REBOA)是一种微创的针对危及生命的腹部或骨盆出血的损伤控制性手术。本综述旨在总结 REBOA 的现有认识和经验,概述该技术的潜在未来应用,并强调进一步研究的优先领域。

最近的发现

REBOA 是一种实现临时主动脉阻断的可行方法,可由经过适当培训的临床医生在紧急情况下(包括在受伤现场)快速、高度成功地进行。该操作支持中央灌注,控制不可压缩性出血,并可能改善某些严重休克患者群体的生存率;但也存在重大风险,包括缺血性组织损伤和手术并发症。该策略的演变正在探索中,部分主动脉阻断和 REBOA 与体外支持相结合的领域已经有了有前景的概念验证研究。

总结

不可压缩性躯干出血是可预防创伤死亡的主要原因。这些死亡中的大多数发生在受伤后不久,通常在有机会进行明确的出血控制之前。为了显著降低创伤死亡率,需要新的快速止血方法。

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