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由生腰果引起的毒素诱导性自身免疫性肝炎

Toxin-Induced Autoimmune Hepatitis Caused by Raw Cashew Nuts.

作者信息

Crismale James F, Stueck Ashley, Bansal Meena

机构信息

Division of Liver Diseases, Icahn School of Medicine at Mount Sinai, New York, NY.

Department of Pathology, Icahn School of Medicine at Mount Sinai, New York, NY.

出版信息

ACG Case Rep J. 2016 Sep 28;3(4):e133. doi: 10.14309/crj.2016.106. eCollection 2016 Aug.

Abstract

A 64-year-old man with no past medical history presented with abnormally elevated liver enzymes 1 year after developing a diffuse rash thought to be related to eating large quantities of raw cashew nuts. Liver biopsy was performed, which revealed features concerning for drug- or toxin-induced autoimmune hepatitis. The patient began treatment with azathioprine and prednisone, and liver enzymes normalized. We describe a unique case of a toxin-induced autoimmune hepatitis precipitated not by a drug or dietary supplement but by a food product.

摘要

一名64岁无既往病史的男性,在出现被认为与大量食用生腰果有关的弥漫性皮疹1年后,出现肝酶异常升高。进行了肝活检,结果显示有药物或毒素诱导的自身免疫性肝炎的特征。患者开始使用硫唑嘌呤和泼尼松治疗,肝酶恢复正常。我们描述了一例独特的毒素诱导的自身免疫性肝炎病例,其诱发因素不是药物或膳食补充剂,而是一种食品。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6198/5062682/e0451d88b990/CG-CGCR160069F001.jpg

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