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腰椎间盘切除术后短期(2周)与长期(6周)限制活动的效果:一项前瞻性随机对照试验。

The effect of short (2-weeks) versus long (6-weeks) post-operative restrictions following lumbar discectomy: a prospective randomized control trial.

作者信息

Bono Christopher M, Leonard Dana A, Cha Thomas D, Schwab Joseph H, Wood Kirkham B, Harris Mitchel B, Schoenfeld Andrew J

机构信息

Department of Orthopaedic Surgery, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA, 02115, USA.

Department of Orthopaedic Surgery, Massachusetts General Hospital, Harvard Medical School, 55 Fruit Street, Boston, MA, 02114, USA.

出版信息

Eur Spine J. 2017 Mar;26(3):905-912. doi: 10.1007/s00586-016-4821-9. Epub 2016 Nov 2.

Abstract

PURPOSE

We sought to evaluate how short (2-week) versus long (6-week) post-operative restrictions following lumbar discectomy impacted outcomes and reherniation rates for a period up to 1 year following surgery.

METHODS

This study included 108 patients undergoing index lumbar discectomy. Patients were randomized immediately following surgery. Outcomes included back and leg visual analog pain scales (VAS), Oswestry Disability Index (ODI), and reherniation rates at 2-weeks, 6-weeks, 3-months, and 1-year following surgery. Differences in reherniation rates were analyzed using Fisher's exact test. VAS and ODI scores were evaluated using Student's t test.

RESULTS

Six patients (11%) in the 2-week restriction group had a reherniation event and four patients (7%) in the 6-week restriction group experienced a reherniation (p = 0.52). VAS back pain (p < 0.001), leg pain (p < 0.001), and ODI scores (p < 0.001) were significantly improved for both cohorts as compared to baseline at the 2-week time point and remained significantly improved through 1-year [VAS back (p < 0.001); VAS leg (p < 0.001); ODI (p < 0.001)]. No significant differences in ODI, VAS back, or VAS leg scores were detected at any of the time points between the 2- and 6-week restriction groups.

CONCLUSIONS

The results of this randomized trial suggest equivalent clinical outcomes irrespective of the length of post-operative restriction. From a clinical perspective, if patients are deemed at low risk for a reherniation event they may be confidence that early return to activity at 2 weeks will not compromise outcomes and may not adversely impact the risk of reherniation. Level of Evidence II.

摘要

目的

我们试图评估腰椎间盘切除术后短期(2周)与长期(6周)限制活动对术后长达1年的疗效及复发率的影响。

方法

本研究纳入108例行初次腰椎间盘切除术的患者。术后患者立即被随机分组。疗效指标包括术后2周、6周、3个月及1年时的背部和腿部视觉模拟疼痛量表(VAS)评分、Oswestry功能障碍指数(ODI)以及复发率。采用Fisher精确检验分析复发率的差异。使用Student t检验评估VAS和ODI评分。

结果

2周限制活动组有6例患者(11%)出现复发事件,6周限制活动组有4例患者(7%)复发(p = 0.52)。与基线相比,两组患者在术后2周时VAS背痛评分(p < 0.001)、腿痛评分(p < 0.001)及ODI评分(p < 0.001)均显著改善,且至1年时仍保持显著改善[VAS背痛(p < 0.001);VAS腿痛(p < 0.001);ODI(p < 0.001)]。2周和6周限制活动组在任何时间点的ODI、VAS背痛或VAS腿痛评分均无显著差异。

结论

这项随机试验的结果表明,无论术后限制活动的时长如何,临床疗效相当。从临床角度来看,如果患者被认为复发风险较低,那么他们可以放心,术后2周尽早恢复活动不会影响疗效,也可能不会对复发风险产生不利影响。证据等级为II级。

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