Yu Hainan, Cancelliere Carol, Mior Silvano, Pereira Paulo, Nordin Margareta, Brunton Ginny, Wong Jessica J, Shearer Heather M, Connell Gaelan, Ead Lauren, Verville Leslie, Rezai Mana, Myrtos Danny, Wang Dan, Marchand Andrée-Anne, Romanelli Andrew, Germann Darrin, To Daphne, Young James J, Southerst Danielle, Candelaria Henry, Hogg-Johnson Sheilah, Côté Pierre
Faculty of Health Sciences, Ontario Tech University, Canada.
Institute for Disability and Rehabilitation Research, Faculty of Health Sciences, Ontario Tech University and Canadian Memorial Chiropractic College, Canada.
Brain Spine. 2024 Apr 16;4:102806. doi: 10.1016/j.bas.2024.102806. eCollection 2024.
The effectiveness of post-surgical rehabilitation following lumbar disc herniation (LDH) surgery is unclear.
To investigate the effectiveness and safety of rehabilitation interventions initiated within three months post-surgery for adults treated surgically for LDH.
This systematic review searched seven databases from inception to November 2023. Independent reviewers screened studies, assessed and extracted data, and rated the certainty of the evidence using the GRADE approach.
This systematic review retrieved 20,531 citations and included 25 randomized controlled trials. The high certainty evidence suggests that adding Pilates exercise to routine care and cognitive behavioral therapy may improve function immediately post-intervention (1 RCT), and that adding whole-body magnetic therapy to exercise, pharmacological and aquatic therapy may reduce low back pain intensity (1 RCT) immediately post-intervention. Compared to placebo, pregabalin did not reduce low back pain or leg pain intensity (1 RCT) (moderate to high certainty evidence). We found no differences between: 1) behavioral graded activity vs. physiotherapy (1 RCT); 2) exercise and education vs. neck massage or watchful waiting (1 RCT); 3) exercise, education, and in-hospital usual care vs. in-hospital usual care (1 RCT); 4) functional or staged exercise vs. usual post-surgical care including exercise (2 RCTs); and 5) supervised exercise with education vs. education (1 RCT). No studies assessed adverse events.
Evidence on effective and safe post-surgical rehabilitation interventions is sparse. This review identified two interventions with potential short-term benefits (Pilates exercises, whole-body magnetic therapy) but safety is unclear, and one with an iatrogenic effect (pregabalin).
腰椎间盘突出症(LDH)手术后的康复效果尚不清楚。
探讨对接受LDH手术治疗的成年人在术后三个月内开始进行康复干预的有效性和安全性。
本系统评价检索了从数据库建立至2023年11月的七个数据库。独立评审员筛选研究、评估和提取数据,并使用GRADE方法对证据的确定性进行评级。
本系统评价检索到20,531条引文,纳入了25项随机对照试验。高确定性证据表明,在常规护理中加入普拉提运动和认知行为疗法可能会在干预后立即改善功能(1项随机对照试验),在运动、药物和水疗中加入全身磁疗可能会在干预后立即降低腰痛强度(1项随机对照试验)。与安慰剂相比,普瑞巴林并未降低腰痛或腿痛强度(1项随机对照试验)(中等至高确定性证据)。我们发现以下方面无差异:1)行为分级活动与物理治疗(1项随机对照试验);2)运动与教育与颈部按摩或观察等待(1项随机对照试验);3)运动、教育和住院常规护理与住院常规护理(1项随机对照试验);4)功能性或分阶段运动与包括运动在内的常规术后护理(2项随机对照试验);5)有教育指导的监督运动与教育(1项随机对照试验)。没有研究评估不良事件。
关于有效且安全的术后康复干预措施的证据稀少。本综述确定了两种具有潜在短期益处的干预措施(普拉提运动、全身磁疗),但安全性尚不清楚,以及一种具有医源性效应的干预措施(普瑞巴林)。