Sabzi Feridoun, Faraji Reza
Preventive Cardiovascular Research Centre Kermanshah, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Natl Med J India. 2016 May-Jun;29(3):146-147.
The most common cardiovascular presentation of brucellosis (a zoonotic infection) in Iran is aortic valve endocarditis. Brucellosis is a systemic infection and may involve any congenital heart defect with various clinical signs and symptoms. We report brucella endocarditis in an atrial septal defect (ASD) in a 55-year-old man who presented with fever and hemiplegia. Echocardiography showed a secundum ASD with large vegetations of 0.5×1 cm arising from the rim of the ASD. Serological analysis was positive for Brucella agglutinin, thus confirming the diagnosis. The brain CT scan revealed a large ischaemic zone in the left hemisphere. At surgery, large vegetations were excised and the defect was closed with fresh pericardium. After surgery the patient was treated with a 4- week course of antibiotics. His recovery was uneventful except for the neurological deficit (hemiplegia); he was discharged on postoperative day 35.
在伊朗，布鲁氏菌病（一种人畜共患感染病）最常见的心血管表现是主动脉瓣心内膜炎。布鲁氏菌病是一种全身性感染，可能累及任何先天性心脏缺陷，并伴有各种临床体征和症状。我们报告了一名55岁男性，患有房间隔缺损（ASD），出现发热和偏瘫，诊断为布鲁氏菌性心内膜炎。超声心动图显示继发孔型房间隔缺损，在缺损边缘有大小为0.5×1厘米的大赘生物。血清学分析布鲁氏菌凝集素呈阳性，从而确诊。脑部CT扫描显示左半球有大片缺血区。手术中，切除了大赘生物，并用新鲜心包封闭缺损。术后患者接受了为期4周的抗生素治疗。除了神经功能缺损（偏瘫）外，他恢复顺利；术后第35天出院。
