Ohde Dalledone Giuliano, Lenci Marques Gustavo, Dal-Prá Ducci Renata, Laffitte Stier Junior Arnaldo, Kay Cláudia Suemi Kamoi, Cesar Werneck Lineu, José Lorenzoni Paulo, Herminia Scola Rosana
Service of Cardiology, Department of Internal Medicine, Hospital de Clínicas, Universidade Federal do Paraná (UFPR), Curitiba, PR, Brazil.
Service of Neuromuscular Disorders, Division of Neurology, Department of Internal Medicine, Hospital de Clínicas, Universidade Federal do Paraná (UFPR), Curitiba, PR, Brazil.
Case Rep Neurol Med. 2016;2016:3589204. doi: 10.1155/2016/3589204. Epub 2016 Oct 16.
Management of cardiac symptoms in myasthenia gravis (MG) patients can be challenging. The aim of this report is to describe the safe use of ivabradine for stable angina in MG patients. A 48 y.o. woman, with MG diagnosis, presented stable angina. Therapies choices were reduced considering concomitant disease as well as previous and unsuccessful cardiologic managements. Ivabradine showed unexpected results. The patient presented an improvement of neurological and cardiac symptoms, bringing ivabradine as one more therapeutic option to similar patients. In this report we recommend ivabradine as an effective and safe drug for treatment of stable angina in MG patients.
重症肌无力（MG）患者心脏症状的管理可能具有挑战性。本报告的目的是描述伊伐布雷定在MG患者稳定型心绞痛中的安全使用情况。一名48岁诊断为MG的女性出现稳定型心绞痛。鉴于合并症以及既往心脏治疗未成功，治疗选择有限。伊伐布雷定显示出意想不到的效果。该患者的神经和心脏症状均有改善，使伊伐布雷定成为类似患者的又一种治疗选择。在本报告中，我们推荐伊伐布雷定作为治疗MG患者稳定型心绞痛的一种有效且安全的药物。
