异种核酸的生物学应用。
Biological applications of xeno nucleic acids.
作者信息
Morihiro Kunihiko, Kasahara Yuuya, Obika Satoshi
机构信息
National Institutes of Biomedical Innovation, Health and Nutrition (NIBIOHN), 7-6-8 Saito-Asagi, Ibaraki, Osaka 567-0085, Japan and Graduate School of Pharmaceutical Sciences, Osaka University, 1-6 Yamadaoka, Suita, Osaka 565-0871, Japan.
出版信息
Mol Biosyst. 2017 Jan 31;13(2):235-245. doi: 10.1039/c6mb00538a.
PMID:27827481
Abstract
Xeno nucleic acids (XNAs) are a group of chemically modified nucleic acid analogues that have been applied to various biological technologies such as antisense oligonucleotides, siRNAs and aptamers.
摘要
异源核酸（XNA）是一类经过化学修饰的核酸类似物，已应用于各种生物技术，如反义寡核苷酸、小干扰RNA（siRNA）和适体。
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